Annotation & Prediction

Ensembl GRCh37 creates automated annotation on human only - for other species, please visit our main site at

Ensembl annotation

Protein-coding genes are automatically annotated using Ensembl's genebuild pipeline. All transcripts are based on mRNA and proteins in public scientific databases.


The Ensembl Variation database stores areas of the genome that differ between individual genomes ("variants") and, where available, associated disease and phenotype information.


Ensembl Regulation provides resources describing the mechanisms of gene regulation in human cells. In particular, it focuses on transcriptional and post-transcriptional mechanisms.