Description
tryptophan hydroxylase 1 [Source:HGNC Symbol;Acc:12008]
Gene Synonyms
TPH, TPRH, TRPH
Location
Chromosome 11: 18,039,111-18,063,973 reverse strand.
GRCh37:CM000673.1
About this gene
This gene has 5 transcripts (splice variants), 253 orthologues and 3 paralogues.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000250018.2 | TPH1-001 | 5325 | 444aa | ENSP00000250018.2 | Protein coding | CCDS7829 | B3VRW5 B3VRX0 B3VRX5 B3VRY0 B3VRY5 B3VRZ0 B3VRZ5 B3VS00 B3VS05 B3VS10 P17752 | NM_004179.2 | Ensembl Canonical, GENCODE Basic, |
| ENST00000341556.2 | TPH1-201 | 1427 | 466aa | ENSP00000343550.2 | Protein coding | B3VRW5 B3VRX0 B3VRX5 B3VRY0 B3VRY5 B3VRZ5 B3VS00 B3VS05 B3VS10 P17752 | - | GENCODE Basic, | |
| ENST00000528338.1 | TPH1-004 | 556 | 165aa | ENSP00000436081.1 | Protein coding | B3VRX5 B3VRY0 B3VRY5 E9PR49 | - | CDS 3' incomplete, | |
| ENST00000417164.1 | TPH1-002 | 1138 | 206aa | ENSP00000403831.1 | Nonsense mediated decay | B3VRX0 B3VRX5 B3VRY0 B3VRY5 E7EMX4 | - | - | |
| ENST00000525406.1 | TPH1-003 | 461 | No protein | - | Processed transcript | - | - | - |
