Description
topoisomerase (DNA) III alpha [Source:HGNC Symbol;Acc:11992]
Gene Synonyms
TOP3
Location
Chromosome 17: 18,174,742-18,218,321 reverse strand.
GRCh37:CM000679.1
About this gene
This gene has 21 transcripts (splice variants), 1 paralogue and is associated with 3 phenotypes.
Transcripts
Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|---|
ENST00000321105.5 | TOP3A-001 | 4056 | 1001aa | ENSP00000321636.5 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS11194 | A8K398 B4DSJ0 Q13472 | NM_004618.3 | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
ENST00000542570.1 | TOP3A-202 | 3156 | 906aa | ENSP00000442336.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | A8K398 B4DK80 B4DSJ0 | - | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, | |
ENST00000580095.1 | TOP3A-020 | 2929 | 976aa | ENSP00000462790.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | A8K398 B4DSJ0 Q13472 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
ENST00000540524.1 | TOP3A-201 | 1951 | 531aa | ENSP00000446425.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | A8K398 B4DSJ0 | - | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, | |
ENST00000489131.1 | TOP3A-008 | 582 | 25aa | ENSP00000465864.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
ENST00000584582.1 | TOP3A-010 | 3661 | 69aa | ENSP00000462136.1 | Nonsense mediated decay | J3KRR9 | - | - | |
ENST00000582981.1 | TOP3A-009 | 3239 | 89aa | ENSP00000462378.1 | Nonsense mediated decay | J3KS96 | - | - | |
ENST00000461127.1 | TOP3A-004 | 823 | 139aa | ENSP00000464338.1 | Nonsense mediated decay | J3QR18 | - | - | |
ENST00000581536.1 | TOP3A-012 | 766 | 163aa | ENSP00000466641.1 | Nonsense mediated decay | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
ENST00000585031.1 | TOP3A-015 | 575 | 95aa | ENSP00000464493.1 | Nonsense mediated decay | J3QS25 | - | - | |
ENST00000582122.1 | TOP3A-019 | 553 | 133aa | ENSP00000466099.1 | Nonsense mediated decay | K7ELI7 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
ENST00000493648.1 | TOP3A-007 | 503 | 52aa | ENSP00000465014.1 | Nonsense mediated decay | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
ENST00000582230.1 | TOP3A-017 | 588 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
ENST00000584669.1 | TOP3A-011 | 580 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
ENST00000584887.1 | TOP3A-016 | 545 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
ENST00000469739.2 | TOP3A-003 | 3196 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
ENST00000583804.2 | TOP3A-013 | 1465 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
ENST00000472959.1 | TOP3A-005 | 913 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
ENST00000583328.1 | TOP3A-018 | 727 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
ENST00000477508.1 | TOP3A-006 | 600 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
ENST00000580713.1 | TOP3A-014 | 474 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |