Transcript: ENST00000398665.3 DOT1L-001

Description

DOT1-like histone H3K79 methyltransferase [Source:HGNC Symbol;Acc:24948]

Gene Synonyms

DOT1, KIAA1814, KMT4

Location

Chromosome 19: 2,164,148-2,232,577 forward strand.

About this transcript

This transcript has 28 exons, is annotated with 20 domains and features, is associated with 43251 variant alleles and maps to 958 oligo probes.

Gene

This transcript is a product of gene ENSG00000104885.13 Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000398665.3	DOT1L-001	7436	1537aa	ENSP00000381657.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS42460	Q8TEK3	NM_032482.2	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000457590.1	DOT1L-008	2906	653aa	ENSP00000407411.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		H7C2S2	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000586024.1	DOT1L-009	725	142aa	ENSP00000476469.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000452696.1	DOT1L-003	624	208aa	ENSP00000404284.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		C9JH95	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000446286.1	DOT1L-007	376	125aa	ENSP00000412916.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		H7C3N3	-	5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete,
ENST00000608122.1	DOT1L-012	576	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000591498.1	DOT1L-010	567	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000482433.1	DOT1L-002	3658	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000478937.2	DOT1L-004	638	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000609690.1	DOT1L-006	393	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000472540.1	DOT1L-005	360	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Summary

Statistics

Exons: 28, Coding exons: 28, Transcript length: 7,436 bps, Translation length: 1,537 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: Q8TEK3

CCDS

This transcript is a member of the Human CCDS set: CCDS42460

Version

ENST00000398665.3

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Transcript having exact match between ENSEMBL and HAVANA:	OTTHUMT00000318066 (version 1)

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

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Transcript: ENST00000398665.3 DOT1L-001

Summary