Transcript: ENST00000353533.5 MAP2K4-001

Description

mitogen-activated protein kinase kinase 4 [Source:HGNC Symbol;Acc:6844]

Gene Synonyms

JNKK, JNKK1, MAPKK4, MEK4, MKK4, PRKMK4, SAPKK-1, SAPKK1, SEK1, SERK1, SKK1

Location

Chromosome 17: 11,924,141-12,047,140 forward strand.

About this transcript

This transcript has 11 exons, is annotated with 11 domains and features, is associated with 53565 variant alleles and maps to 728 oligo probes.

Gene

This transcript is a product of gene ENSG00000065559.10 Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000353533.5	MAP2K4-001	3826	399aa	ENSP00000262445.5	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS11162	J3KTI6 J3QQR2 P45985	NM_003010.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000415385.3	MAP2K4-002	3856	410aa	ENSP00000410402.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS62095	J3KTI6 J3QQR2 P45985	NM_001281435.1	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000602811.1	MAP2K4-011	1136	41aa	ENSP00000473582.1	Nonsense mediated decay		R4GN68	-	-
ENST00000602375.1	MAP2K4-012	1064	92aa	ENSP00000473472.1	Nonsense mediated decay		R4GN37	-	-
ENST00000602686.1	MAP2K4-014	977	41aa	ENSP00000473458.1	Nonsense mediated decay		R4GN68	-	-
ENST00000602305.1	MAP2K4-013	961	45aa	ENSP00000473606.1	Nonsense mediated decay		J3QLE2	-	-
ENST00000602537.1	MAP2K4-015	948	41aa	ENSP00000473511.1	Nonsense mediated decay		R4GN68	-	-
ENST00000538465.3	MAP2K4-008	925	16aa	ENSP00000467239.1	Nonsense mediated decay		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000582183.1	MAP2K4-010	551	45aa	ENSP00000463507.1	Nonsense mediated decay		J3QLE2	-	-
ENST00000581941.1	MAP2K4-003	813	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000579089.1	MAP2K4-009	571	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000582897.1	MAP2K4-006	482	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000536413.2	MAP2K4-005	3852	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000582377.1	MAP2K4-004	648	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000585076.1	MAP2K4-007	543	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Summary

Statistics

Exons: 11, Coding exons: 11, Transcript length: 3,826 bps, Translation length: 399 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: P45985

CCDS

This transcript is a member of the Human CCDS set: CCDS11162

Version

ENST00000353533.5

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Transcript having exact match between ENSEMBL and HAVANA:	OTTHUMT00000441226 (version 1)

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

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Transcript: ENST00000353533.5 MAP2K4-001

Summary