Description
interleukin-1 receptor-associated kinase 4 [Source:HGNC Symbol;Acc:17967]
Gene Synonyms
IPD1, IRAK-4, NY-REN-64, REN64
Location
Chromosome 12: 44,152,747-44,183,346 forward strand.
GRCh37:CM000674.1
About this gene
This gene has 13 transcripts (splice variants), 3 paralogues and is associated with 3 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000448290.2 | IRAK4-001 | 2835 | 460aa | ENSP00000390651.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS8744 | F8VR40 F8VW24 Q69FE3 Q9NWZ3 | NM_016123.3 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000431837.1 | IRAK4-201 | 4147 | 336aa | ENSP00000390327.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS44862 | Q9NWZ3 | NM_001145257.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000551736.1 | IRAK4-002 | 1684 | 460aa | ENSP00000446490.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS8744 | F8VR40 F8VW24 Q69FE3 Q9NWZ3 | NM_001114182.2 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000440781.2 | IRAK4-005 | 1409 | 336aa | ENSP00000408734.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS44862 | Q9NWZ3 | NM_001145258.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000550616.1 | IRAK4-011 | 547 | 89aa | ENSP00000446571.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F8VR40 F8VW24 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000547521.1 | IRAK4-007 | 1757 | 60aa | ENSP00000449693.1 | Nonsense mediated decay | F8VVZ1 F8VW24 | - | - | |
| ENST00000550386.1 | IRAK4-003 | 1751 | 54aa | ENSP00000449848.1 | Nonsense mediated decay | F8VW24 | - | - | |
| ENST00000547101.1 | IRAK4-004 | 1703 | 54aa | ENSP00000449317.1 | Nonsense mediated decay | F8VW24 | - | - | |
| ENST00000550615.1 | IRAK4-006 | 1348 | 60aa | ENSP00000449553.1 | Nonsense mediated decay | F8VVZ1 F8VW24 | - | - | |
| ENST00000552309.1 | IRAK4-010 | 1000 | 60aa | ENSP00000448197.1 | Nonsense mediated decay | F8VVZ1 F8VW24 | - | - | |
| ENST00000550361.1 | IRAK4-008 | 563 | 60aa | ENSP00000449859.1 | Nonsense mediated decay | F8VVZ1 F8VW24 | - | - | |
| ENST00000547928.1 | IRAK4-012 | 626 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000546780.1 | IRAK4-009 | 540 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
