Human (GRCh37.p13)
Description

mitogen-activated protein kinase kinase 4 [Source:HGNC Symbol;Acc:6844]

Gene Synonyms

JNKK, JNKK1, MAPKK4, MEK4, MKK4, PRKMK4, SAPKK-1, SAPKK1, SEK1, SERK1, SKK1

Location

Chromosome 17: 11,924,141-12,047,147 forward strand.

GRCh37:CM000679.1

About this gene

This gene has 15 transcripts (splice variants), 6 paralogues and is associated with 65 phenotypes.

Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeqFlags
ENST00000353533.5MAP2K4-0013826399aaENSP00000262445.5
 
Protein coding
CCDS11162J3KTI6 J3QQR2 P45985
NM_003010.3Ensembl CanonicalGENCODE Basic
ENST00000415385.3MAP2K4-0023856410aaENSP00000410402.3
 
Protein coding
CCDS62095J3KTI6 J3QQR2 P45985
NM_001281435.1GENCODE Basic
ENST00000602811.1MAP2K4-011113641aaENSP00000473582.1
 
Nonsense mediated decay
R4GN68 --
ENST00000602375.1MAP2K4-012106492aaENSP00000473472.1
 
Nonsense mediated decay
R4GN37 --
ENST00000602686.1MAP2K4-01497741aaENSP00000473458.1
 
Nonsense mediated decay
R4GN68 --
ENST00000602305.1MAP2K4-01396145aaENSP00000473606.1
 
Nonsense mediated decay
J3QLE2 --
ENST00000602537.1MAP2K4-01594841aaENSP00000473511.1
 
Nonsense mediated decay
R4GN68 --
ENST00000538465.3MAP2K4-00892516aaENSP00000467239.1
 
Nonsense mediated decay
--CDS 5' incomplete
ENST00000582183.1MAP2K4-01055145aaENSP00000463507.1
 
Nonsense mediated decay
J3QLE2 --
ENST00000581941.1MAP2K4-003813No protein-
 
Processed transcript
---
ENST00000579089.1MAP2K4-009571No protein-
 
Processed transcript
---
ENST00000582897.1MAP2K4-006482No protein-
 
Processed transcript
---
ENST00000536413.2MAP2K4-0053852No protein-
 
Retained intron
---
ENST00000582377.1MAP2K4-004648No protein-
 
Retained intron
---
ENST00000585076.1MAP2K4-007543No protein-
 
Retained intron
---