Description
ribosomal protein S6 kinase, 70kDa, polypeptide 1 [Source:HGNC Symbol;Acc:10436]
Gene Synonyms
PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70 S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha
Location
Chromosome 17: 57,970,447-58,027,925 forward strand.
GRCh37:CM000679.1
About this gene
This gene has 12 transcripts (splice variants) and 15 paralogues.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000225577.4 | RPS6KB1-001 | 5375 | 525aa | ENSP00000225577.4 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS11621 | B4DLT4 K7EIM2 P23443 | NM_003161.3 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000393021.3 | RPS6KB1-201 | 2046 | 472aa | ENSP00000376744.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS62273 | B4DLT4 K7EIM2 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000406116.3 | RPS6KB1-002 | 1982 | 451aa | ENSP00000384335.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS62271 | K7EIM2 Q7Z721 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000443572.2 | RPS6KB1-008 | 1913 | 502aa | ENSP00000441993.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS62272 | F6UYM1 | NM_001272042.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000592726.1 | RPS6KB1-007 | 622 | 62aa | ENSP00000464805.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | K7EIM2 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000472940.1 | RPS6KB1-003 | 2808 | 140aa | ENSP00000468058.1 | Nonsense mediated decay | K7EIM2 K7ER06 | - | - | |
| ENST00000489824.1 | RPS6KB1-004 | 909 | 52aa | ENSP00000466562.1 | Nonsense mediated decay | K7EMM2 | - | - | |
| ENST00000587061.1 | RPS6KB1-011 | 564 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000477179.1 | RPS6KB1-005 | 431 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000590928.1 | RPS6KB1-010 | 720 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000475155.1 | RPS6KB1-006 | 719 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000587622.1 | RPS6KB1-009 | 583 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
