Description
nucleotide-binding oligomerization domain containing 2 [Source:HGNC Symbol;Acc:5331]
Gene Synonyms
ACUG, BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, NOD2B, PSORAS1
Location
Chromosome 16: 50,727,514-50,766,988 forward strand.
GRCh37:CM000678.1
About this gene
This gene has 10 transcripts (splice variants), 6 paralogues and is associated with 9 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000300589.2 | NOD2-001 | 4486 | 1040aa | ENSP00000300589.2 | Protein coding | CCDS10746 | A3FA72 A7J384 A7KZQ9 A7KZR0 B5A7D5 B5B2Z4 B5B2Z5 B5B2Z6 D6CHF9 D9N2T7 E9PK30 Q6TDC3 Q7Z596 Q7Z597 Q9HC29 | NM_022162.1 | Ensembl Canonical, GENCODE Basic, |
| ENST00000531674.1 | NOD2-004 | 624 | 146aa | ENSP00000431681.1 | Protein coding | A3FA72 E9PK30 Q6TDC3 | - | CDS 3' incomplete, | |
| ENST00000534057.1 | NOD2-010 | 506 | 169aa | ENSP00000437246.1 | Protein coding | B5B2Z5 B5B2Z6 Q7Z596 | - | CDS 5' and 3' incomplete, | |
| ENST00000527070.1 | NOD2-002 | 1707 | 35aa | ENSP00000435149.1 | Nonsense mediated decay | E9PLF7 | - | - | |
| ENST00000534067.1 | NOD2-006 | 602 | 60aa | ENSP00000463145.1 | Nonsense mediated decay | B5B2Z5 | - | CDS 5' incomplete, | |
| ENST00000529633.1 | NOD2-007 | 450 | 60aa | ENSP00000462443.1 | Nonsense mediated decay | B5B2Z5 | - | CDS 5' incomplete, | |
| ENST00000524712.1 | NOD2-008 | 366 | 60aa | ENSP00000464065.1 | Nonsense mediated decay | B5B2Z5 | - | CDS 5' incomplete, | |
| ENST00000527052.1 | NOD2-009 | 338 | 60aa | ENSP00000463423.1 | Nonsense mediated decay | B5B2Z5 | - | CDS 5' incomplete, | |
| ENST00000526417.2 | NOD2-003 | 1100 | No protein | - | Processed transcript | - | - | - | |
| ENST00000532206.1 | NOD2-005 | 878 | No protein | - | Processed transcript | - | - | - |
