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Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
- Paralogues
- Genomic alignments
- Gene tree
- Gene gain/loss tree
- Orthologues
Ontologies
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: HMGCR ENSG00000113161

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Description

3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]

Gene Synonyms

LDLCQ3

Location

Chromosome 5: 74,632,154-74,657,929 forward strand.

GRCh37:CM000667.1

About this gene

This gene has 13 transcripts (splice variants) and is associated with 1 phenotype.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000287936.4	HMGCR-001	4585	888aa	ENSP00000287936.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS4027	C9JKX7 D6RIW0 P04035	NM_000859.2	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000343975.5	HMGCR-004	3681	835aa	ENSP00000340816.5	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS47234	C9JKX7 D6RIW0 P04035	NM_001130996.1	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000511206.1	HMGCR-002	3395	888aa	ENSP00000426745.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS4027	C9JKX7 D6RIW0 P04035	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000509085.1	HMGCR-005	637	165aa	ENSP00000421378.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000507942.1	HMGCR-009	527	111aa	ENSP00000427340.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		C9JKX7 D6RIW0	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000511986.1	HMGCR-006	487	115aa	ENSP00000420871.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		H0Y8F6	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000442032.2	HMGCR-010	268	18aa	ENSP00000409100.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		C9JKX7	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000504466.1	HMGCR-007	1107	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000514315.2	HMGCR-013	603	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000515776.1	HMGCR-012	501	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000512053.1	HMGCR-014	465	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000508070.1	HMGCR-011	450	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000509431.1	HMGCR-008	421	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Summary

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