Description
mitogen-activated protein kinase kinase kinase 3 [Source:HGNC Symbol;Acc:6855]
Gene Synonyms
MAPKKK3, MEKK3
Location
Chromosome 17: 61,699,775-61,773,663 forward strand.
GRCh37:CM000679.1
About this gene
This gene has 11 transcripts (splice variants) and 7 paralogues.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000361357.3 | MAP3K3-001 | 4818 | 657aa | ENSP00000354927.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS32701 | Q7Z4E6 Q99759 | NM_203351.1 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000361733.3 | MAP3K3-004 | 3529 | 626aa | ENSP00000354485.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS32702 | Q7Z4E6 Q96HN9 Q99759 | NM_002401.3 | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000579585.1 | MAP3K3-007 | 3352 | 657aa | ENSP00000461988.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS32701 | Q7Z4E6 Q99759 | - | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000584573.1 | MAP3K3-002 | 2480 | 653aa | ENSP00000464130.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | J3QRB6 Q7Z4E6 | - | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, | |
| ENST00000577395.1 | MAP3K3-005 | 2016 | 622aa | ENSP00000462086.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | J3KRN4 Q7Z4E6 | - | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, | |
| ENST00000577597.1 | MAP3K3-006 | 2024 | 56aa | ENSP00000462917.1 | Nonsense mediated decay | J3KTC4 | - | - | |
| ENST00000585302.1 | MAP3K3-008 | 678 | 31aa | ENSP00000464532.1 | Nonsense mediated decay | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000581732.1 | MAP3K3-010 | 580 | 42aa | ENSP00000464482.1 | Nonsense mediated decay | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000577784.1 | MAP3K3-011 | 565 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000577839.1 | MAP3K3-012 | 594 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000578622.1 | MAP3K3-009 | 560 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
