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Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: FURIN ENSG00000140564

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Description

furin (paired basic amino acid cleaving enzyme) [Source:HGNC Symbol;Acc:8568]

Gene Synonyms

FUR, PACE, PCSK3, SPC1

Location

Chromosome 15: 91,411,822-91,426,688 forward strand.

GRCh37:CM000677.1

About this gene

This gene has 5 transcripts (splice variants) and 6 paralogues.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000268171.3	FURIN-001	4244	794aa	ENSP00000268171.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS10364	H0YKB2 H0YNB5 P09958	NM_002569.2	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000559353.1	FURIN-003	587	69aa	ENSP00000452730.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		H0YKB2	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000560824.1	FURIN-005	580	175aa	ENSP00000453212.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		H0YKB2 H0YLH7	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000558794.1	FURIN-002	844	216aa	ENSP00000453942.1	Nonsense mediated decay		H0YNB5	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000560018.1	FURIN-004	421	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Summary

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