Description
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:16712]
Gene Synonyms
AGO, CDC4, FBW6, FBW7, FBX30, FBXO30, FBXW6, FLJ11071, SEL-10, SEL10, hAgo, hCdc4
Location
Chromosome 4: 153,242,410-153,457,253 reverse strand.
GRCh37:CM000666.1
About this gene
This gene has 13 transcripts (splice variants), 6 paralogues and is associated with 104 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000281708.4 | FBXW7-001 | 4977 | 707aa | ENSP00000281708.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS3777 | A7BJS8 G0Z2K0 H9CWI2 H9CWI3 Q969H0 S4R3N3 | NM_033632.3 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000263981.5 | FBXW7-005 | 3743 | 627aa | ENSP00000263981.4 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS3778 | A7BJS8 H9CWI2 H9CWI3 Q59ET6 Q969H0 | NM_018315.4 | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000296555.5 | FBXW7-003 | 3572 | 589aa | ENSP00000296555.4 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS34078 | A7BJS8 H9CWI2 H9CWI3 Q969H0 | NM_001013415.1 | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000603548.1 | FBXW7-002 | 2562 | 707aa | ENSP00000474725.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS3777 | A7BJS8 G0Z2K0 H9CWI2 H9CWI3 Q969H0 S4R3N3 | - | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000603841.1 | FBXW7-012 | 2261 | 707aa | ENSP00000474971.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS3777 | A7BJS8 G0Z2K0 H9CWI2 H9CWI3 Q969H0 S4R3N3 | - | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000393956.3 | FBXW7-007 | 1735 | 531aa | ENSP00000377528.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | A7BJS8 B7Z2C8 H9CWI2 H9CWI3 | - | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, | |
| ENST00000604872.1 | FBXW7-004 | 970 | 176aa | ENSP00000474751.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS64082 | G0Z2K0 S4R3N3 S4R3U4 | NM_001257069.1 | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000605042.1 | FBXW7-013 | 671 | 158aa | ENSP00000474538.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | G0Z2K0 S4R3N3 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000604095.1 | FBXW7-014 | 755 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000603821.1 | FBXW7-008 | 4279 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000604069.1 | FBXW7-010 | 615 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000604822.1 | FBXW7-009 | 570 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000604316.1 | FBXW7-011 | 528 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |