Gene: MAP3K8 ENSG00000107968

Description

mitogen-activated protein kinase kinase kinase 8 [Source:HGNC Symbol;Acc:6860]

Gene Synonyms

COT, EST, ESTF, MEKK8, TPL2, Tpl-2, c-COT

Location

Chromosome 10: 30,722,866-30,750,762 forward strand.

GRCh37:CM000672.1

About this gene

This gene has 7 transcripts (splice variants) and 7 paralogues.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000263056.1	MAP3K8-002	3096	467aa	ENSP00000263056.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS7166	P41279 Q5T853 Q5T857	NM_005204.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000375321.1	MAP3K8-003	2518	467aa	ENSP00000364470.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS7166	P41279 Q5T853 Q5T857	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000542547.1	MAP3K8-201	1682	467aa	ENSP00000443610.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS7166	P41279 Q5T853 Q5T857	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000415139.1	MAP3K8-004	1026	255aa	ENSP00000409653.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q5T853 Q5T857	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000375322.2	MAP3K8-006	932	132aa	ENSP00000364471.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q5T854	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000413724.1	MAP3K8-005	776	223aa	ENSP00000391275.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q5T853	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000430603.1	MAP3K8-001	647	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Genomic alignments

As of the latest update in March 2020 we are not supporting data for species other than human on this GRCh37 site and the view you wish to use is disabled.

You can read more about why we have done this on our blog.

You can still view this page on the following archive resources:

1. The Ensembl 75 archive represents a code and data freeze taken in February 2014.

2. The GRCh37 archive represents a code and data freeze taken in January 2019.

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Recent locations

Gene: MAP3K8 ENSG00000107968

Genomic alignments