Transcript: ENST00000228740.2 LTA4H-001

Description

leukotriene A4 hydrolase [Source:HGNC Symbol;Acc:6710]

Gene Synonyms

LTA4

Location

Chromosome 12: 96,394,606-96,429,439 reverse strand.

About this transcript

This transcript has 19 exons, is annotated with 15 domains and features, is associated with 13200 variant alleles and maps to 624 oligo probes.

Gene

This transcript is a product of gene ENSG00000111144.5 Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000228740.2	LTA4H-001	2139	611aa	ENSP00000228740.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS9059	P09960 Q49AK0	NM_000895.2	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000552789.1	LTA4H-003	2025	587aa	ENSP00000449958.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS58267	P09960 Q49AK0	NM_001256643.1	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000413268.2	LTA4H-002	1908	508aa	ENSP00000395051.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS58266	P09960	NM_001256644.1	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000548852.1	LTA4H-004	1810	132aa	ENSP00000449340.1	Nonsense mediated decay		B4DEH5	-	-
ENST00000548375.1	LTA4H-010	639	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000553041.1	LTA4H-007	6109	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000537111.2	LTA4H-009	1881	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000547982.1	LTA4H-008	986	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000552091.1	LTA4H-012	595	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000547393.1	LTA4H-011	543	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Summary

Statistics

Exons: 19, Coding exons: 19, Transcript length: 2,139 bps, Translation length: 611 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: P09960

CCDS

This transcript is a member of the Human CCDS set: CCDS9059

Version

ENST00000228740.2

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

Stop codons

This transcript has a variant, rs2228061, that causes a stop codon to be gained in at least 10% of HapMap or 1000 Genome population(s) CSHL-HAPMAP:HAPMAP-MKK, CSHL-HAPMAP:HapMap-YRI, CSHL-HAPMAP:HAPMAP-MEX, CSHL-HAPMAP:HAPMAP-CHD, CSHL-HAPMAP:HAPMAP-ASW, CSHL-HAPMAP:HAPMAP-LWK.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Transcript having exact match between ENSEMBL and HAVANA:	OTTHUMT00000408655 (version 1)

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

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Transcript: ENST00000228740.2 LTA4H-001

Summary