Description

breast cancer 2, early onset [Source:HGNC Symbol;Acc:1101]

Synonyms

FANCB, BROVCA2, FACD, FANCD, BRCC2, PNCA2, FAD, GLM3, FAD1, FANCD1

Location

Chromosome 13: 32,889,611-32,973,805 forward strand.

GRCh37:CM000675.1

About this gene

This gene has 6 transcripts (splice variants), 61 orthologues, is a member of 2 Ensembl protein families and is associated with 60 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
BRCA2-201ENST00000544455.1109843418aaENSP00000439902
 
Protein coding
CCDS9344E9PIQ1 K4JTT2 K4JXT6
K4K7W0 P51587 Q8IU64
Q8IU77 Q8IU82 Q9H4L3
NM_000059
NP_000050
GENCODE basic
BRCA2-001ENST00000380152.3109303418aaENSP00000369497
 
Protein coding
CCDS9344E9PIQ1 K4JTT2 K4JXT6
K4K7W0 P51587 Q8IU64
Q8IU77 Q8IU82 Q9H4L3
-GENCODE basic
BRCA2-003ENST00000530893.22011481aaENSP00000435699
 
Protein coding
-E9PIQ1 Q8IU82 -CDS 3' incomplete
BRCA2-002ENST00000470094.1842186aaENSP00000434898
 
Nonsense mediated decay
---CDS 5' incomplete
BRCA2-005ENST00000528762.149564aaENSP00000433168
 
Nonsense mediated decay
-H0YD86 -CDS 5' incomplete
BRCA2-006ENST00000533776.1523No protein-
 
Retained intron
---

Gene-based displays