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Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: DHFR ENSG00000228716

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Description

dihydrofolate reductase [Source:HGNC Symbol;Acc:2861]

Gene Synonyms

DHFRP1, DYR

Location

Chromosome 5: 79,922,047-79,950,802 reverse strand.

GRCh37:CM000667.1

About this gene

This gene has 7 transcripts (splice variants), 1 paralogue and is associated with 4 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000439211.2	DHFR-001	3917	187aa	ENSP00000396308.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS47240	B0YJ76 B4DDD2 P00374	NM_000791.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000505337.1	DHFR-006	1719	187aa	ENSP00000426474.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS47240	B0YJ76 B4DDD2 P00374	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000511032.1	DHFR-005	1474	129aa	ENSP00000422732.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B4DM58	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000504396.1	DHFR-003	1447	135aa	ENSP00000421334.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B4DDD2	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000513048.1	DHFR-004	994	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000513314.1	DHFR-008	582	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000508282.1	DHFR-007	545	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Summary

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