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Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: STK11 ENSG00000118046

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Description

serine/threonine kinase 11 [Source:HGNC Symbol;Acc:11389]

Gene Synonyms

LKB1, PJS, hLKB1

Location

Chromosome 19: 1,189,406-1,228,428 forward strand.

GRCh37:CM000681.1

About this gene

This gene has 9 transcripts (splice variants), 2 paralogues and is associated with 79 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000326873.7	STK11-001	3328	433aa	ENSP00000324856.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS45896	Q15831 Q9NS52	NM_000455.4	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000586243.1	STK11-009	844	282aa	ENSP00000467240.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete,
ENST00000585851.1	STK11-004	505	153aa	ENSP00000467912.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		K7EQN8	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000593219.1	STK11-008	1338	101aa	ENSP00000466610.1	Nonsense mediated decay		K7EMR0	-	-
ENST00000585748.1	STK11-012	400	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000585465.1	STK11-003	3553	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000589152.1	STK11-002	3365	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000591133.1	STK11-006	894	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000586358.1	STK11-005	761	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Summary

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