Gene: TGFB1 ENSG00000105329

Description

transforming growth factor, beta 1 [Source:HGNC Symbol;Acc:11766]

Gene Synonyms

CED, DPD1, LAP, TGFB, TGFbeta

Location

GRCh37:CM000681.1

About this gene

This gene has 4 transcripts (splice variants), 8 paralogues and is associated with 6 phenotypes.

Transcripts

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000221930.5	TGFB1-001	2769	390aa	ENSP00000221930.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS33031	P01137 Q5PY19 Q7Z487 Q7Z488	NM_000660.4	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000598758.1	TGFB1-004	559	120aa	ENSP00000472767.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q7Z487	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000600196.1	TGFB1-003	399	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000597453.1	TGFB1-002	392	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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