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Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: TOP1MT ENSG00000184428

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Description

topoisomerase (DNA) I, mitochondrial [Source:HGNC Symbol;Acc:29787]

Location

Chromosome 8: 144,386,554-144,442,149 reverse strand.

GRCh37:CM000670.1

About this gene

This gene has 19 transcripts (splice variants) and 1 paralogue.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000329245.4	TOP1MT-001	1958	601aa	ENSP00000328835.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS6400	E5KMK7 E5RFS0 E5RJ33 E5RJ95 Q8TBP3 Q969P6	NM_052963.2	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000523676.1	TOP1MT-005	1982	503aa	ENSP00000429181.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS59115	E5RFS0 E5RJ33 E5RJ95 Q8TBP3 Q969P6	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000521193.1	TOP1MT-003	1960	503aa	ENSP00000428369.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS59115	E5RFS0 E5RJ33 E5RJ95 Q8TBP3 Q969P6	NM_001258446.1	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000519148.1	TOP1MT-002	1868	503aa	ENSP00000429169.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS59115	E5RFS0 E5RJ33 E5RJ95 Q8TBP3 Q969P6	NM_001258447.1	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000519139.2	TOP1MT-006	1561	376aa	ENSP00000428451.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E5RFS0 E5RIC7 E5RJ33 E5RJ95	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000519591.1	TOP1MT-016	1007	201aa	ENSP00000429177.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E5RJ33 E5RJ95	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000522041.1	TOP1MT-017	906	221aa	ENSP00000427998.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E5RFS0 E5RJ33 E5RJ95	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000519977.1	TOP1MT-013	892	111aa	ENSP00000427925.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q8TBP3	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000518760.1	TOP1MT-020	613	164aa	ENSP00000428723.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E5RGR4 E5RJ33	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000520950.1	TOP1MT-011	564	33aa	ENSP00000430635.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E5RJ33	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000518007.1	TOP1MT-021	509	134aa	ENSP00000430209.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E5RGE7 E5RJ33	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000522043.1	TOP1MT-015	499	164aa	ENSP00000428931.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E5RFE3	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000518951.2	TOP1MT-007	1461	167aa	ENSP00000428727.1	Nonsense mediated decay		E5RGR2 E5RJ33	-	-
ENST00000522121.1	TOP1MT-018	874	49aa	ENSP00000430139.1	Nonsense mediated decay		H0YBR3	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000523417.1	TOP1MT-019	698	123aa	ENSP00000430679.1	Nonsense mediated decay		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000505857.2	TOP1MT-004	2029	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000521024.1	TOP1MT-010	520	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000524092.1	TOP1MT-014	313	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000517857.1	TOP1MT-012	624	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Summary

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