Description
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) [Source:HGNC Symbol;Acc:6155]
Gene Synonyms
CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7
Location
Chromosome 21: 46,305,868-46,351,904 reverse strand.
GRCh37:CM000683.1
About this gene
This gene has 24 transcripts (splice variants), 9 paralogues and is associated with 2 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000397850.2 | ITGB2-002 | 3178 | 769aa | ENSP00000380948.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS13716 | E5RFI0 E5RHE6 E5RHT0 E5RIG7 E5RK25 E5RK54 E7EVZ9 P05107 Q96PT7 | - | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000302347.5 | ITGB2-201 | 2955 | 769aa | ENSP00000303242.5 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS13716 | E5RFI0 E5RHE6 E5RHT0 E5RIG7 E5RK25 E5RK54 E7EVZ9 P05107 Q96PT7 | NM_000211.3 | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000355153.4 | ITGB2-001 | 2913 | 769aa | ENSP00000347279.4 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS13716 | E5RFI0 E5RHE6 E5RHT0 E5RIG7 E5RK25 E5RK54 E7EVZ9 P05107 Q96PT7 | NM_001127491.1 | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000397857.1 | ITGB2-004 | 2813 | 769aa | ENSP00000380955.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS13716 | E5RFI0 E5RHE6 E5RHT0 E5RIG7 E5RK25 E5RK54 E7EVZ9 P05107 Q96PT7 | - | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000397852.1 | ITGB2-005 | 2769 | 769aa | ENSP00000380950.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS13716 | E5RFI0 E5RHE6 E5RHT0 E5RIG7 E5RK25 E5RK54 E7EVZ9 P05107 Q96PT7 | - | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000397854.3 | ITGB2-003 | 2592 | 712aa | ENSP00000380952.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | A8MYE6 E5RFI0 E5RHE6 E5RHT0 | - | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, | |
| ENST00000320216.6 | ITGB2-010 | 966 | 322aa | ENSP00000317697.6 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RHE6 E5RK54 J3KNI6 Q96PT7 | - | 5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete, | |
| ENST00000523663.1 | ITGB2-024 | 680 | 166aa | ENSP00000428503.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RFI0 E5RHE6 E5RHT0 E5RIG7 E5RK25 E5RK54 E7EVZ9 Q96PT7 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000522688.1 | ITGB2-017 | 606 | 49aa | ENSP00000428125.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RHE6 E5RK54 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000522931.1 | ITGB2-022 | 573 | 160aa | ENSP00000428979.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RFI0 E5RHE6 E5RHT0 E5RIG7 E5RK25 E5RK54 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000517563.1 | ITGB2-015 | 571 | 120aa | ENSP00000428413.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RFI0 E5RHE6 E5RHT0 E5RIG7 E5RK54 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000524251.1 | ITGB2-021 | 568 | 37aa | ENSP00000430901.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RHE6 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000521995.1 | ITGB2-014 | 556 | 49aa | ENSP00000429683.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RHT0 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000517819.1 | ITGB2-016 | 527 | 70aa | ENSP00000428870.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RFI0 E5RHT0 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000397846.3 | ITGB2-008 | 422 | 108aa | ENSP00000380944.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | A8MVG7 E5RHT0 | - | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, | |
| ENST00000523323.1 | ITGB2-013 | 2823 | 71aa | ENSP00000427732.1 | Nonsense mediated decay | E5RGK9 | - | - | |
| ENST00000520389.1 | ITGB2-020 | 568 | 93aa | ENSP00000428434.1 | Nonsense mediated decay | E5RHT0 E5RIE4 | - | - | |
| ENST00000523126.1 | ITGB2-023 | 577 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000521987.1 | ITGB2-018 | 563 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000479849.1 | ITGB2-009 | 427 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000498666.1 | ITGB2-007 | 4781 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000475170.1 | ITGB2-006 | 2125 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000479202.1 | ITGB2-011 | 704 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000518033.1 | ITGB2-019 | 572 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
