Transcript: ENST00000536354.2 TDO2-001

Description

tryptophan 2,3-dioxygenase [Source:HGNC Symbol;Acc:11708]

Gene Synonyms

TDO, TO, TPH2, TRPO

Location

Chromosome 4: 156,824,847-156,841,558 forward strand.

About this transcript

This transcript has 12 exons, is annotated with 8 domains and features, is associated with 7908 variant alleles and maps to 454 oligo probes.

Gene

This transcript is a product of gene ENSG00000151790.4 Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000536354.2	TDO2-001	1701	406aa	ENSP00000444788.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS34086	D6RA50 D6RB68 P48775	NM_005651.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000506072.1	TDO2-006	665	65aa	ENSP00000423394.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		D6RA50 D6RB68	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000507590.1	TDO2-007	557	49aa	ENSP00000424384.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		D6RB68	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000506181.1	TDO2-008	779	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000503634.1	TDO2-005	571	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000510293.1	TDO2-004	379	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000512584.1	TDO2-002	3139	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000509738.1	TDO2-003	935	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Summary

Statistics

Exons: 12, Coding exons: 12, Transcript length: 1,701 bps, Translation length: 406 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: P48775

CCDS

This transcript is a member of the Human CCDS set: CCDS34086

Version

ENST00000536354.2

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Transcript having exact match between ENSEMBL and HAVANA:	OTTHUMT00000366209 (version 3)

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

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Transcript: ENST00000536354.2 TDO2-001

Summary