Transcript: ENST00000590474.1 MAP2K6-001

Description

mitogen-activated protein kinase kinase 6 [Source:HGNC Symbol;Acc:6846]

Gene Synonyms

MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3, SKK3

Location

Chromosome 17: 67,410,839-67,539,472 forward strand.

About this transcript

This transcript has 12 exons, is annotated with 10 domains and features, is associated with 51762 variant alleles and maps to 618 oligo probes.

Gene

This transcript is a product of gene ENSG00000108984.9 Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000590474.1	MAP2K6-001	2870	334aa	ENSP00000468348.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS11686	A8K3Y2 K7ELM6 P52564	NM_002758.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000589647.1	MAP2K6-004	1512	278aa	ENSP00000467213.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		K7ELM6 P52564	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000589295.1	MAP2K6-006	669	84aa	ENSP00000466143.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		K7ELM6	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000588110.1	MAP2K6-008	632	128aa	ENSP00000464916.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		K7EIW3	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000359094.3	MAP2K6-005	1851	68aa	ENSP00000351997.3	Nonsense mediated decay		-	-	-
ENST00000591445.1	MAP2K6-002	3076	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000586641.1	MAP2K6-003	1542	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000592348.1	MAP2K6-007	431	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Summary

Statistics

Exons: 12, Coding exons: 12, Transcript length: 2,870 bps, Translation length: 334 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: P52564

CCDS

This transcript is a member of the Human CCDS set: CCDS11686

Version

ENST00000590474.1

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Transcript having exact match between ENSEMBL and HAVANA:	OTTHUMT00000450689 (version 1)

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

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Transcript: ENST00000590474.1 MAP2K6-001

Summary