Transcript: ENST00000394053.2 MTHFD2-001

Description

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [Source:HGNC Symbol;Acc:7434]

Gene Synonyms

NMDMC

Location

Chromosome 2: 74,425,689-74,444,692 forward strand.

About this transcript

This transcript has 8 exons, is annotated with 20 domains and features, is associated with 9045 variant alleles and maps to 654 oligo probes.

Gene

This transcript is a product of gene ENSG00000065911.7 Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000394053.2	MTHFD2-001	4456	350aa	ENSP00000377617.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS1935	B2R7W0 B4DY35 P13995 Q7Z650	NM_006636.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000409601.1	MTHFD2-009	1865	267aa	ENSP00000386542.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B8ZZU9	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000409804.1	MTHFD2-003	1757	222aa	ENSP00000386536.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B9A062	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000264090.4	MTHFD2-201	1396	248aa	ENSP00000264090.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B4DY35 Q7Z650	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000394050.3	MTHFD2-202	1135	186aa	ENSP00000377614.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B4DY35	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000470592.1	MTHFD2-007	1396	37aa	ENSP00000419067.1	Nonsense mediated decay		F8WF89	-	-
ENST00000489041.1	MTHFD2-008	1135	36aa	ENSP00000419550.1	Nonsense mediated decay		F8WF06	-	-
ENST00000477455.1	MTHFD2-004	696	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000462026.1	MTHFD2-006	599	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000488086.1	MTHFD2-005	483	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-

Summary

Statistics

Exons: 8, Coding exons: 8, Transcript length: 4,456 bps, Translation length: 350 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: P13995

CCDS

This transcript is a member of the Human CCDS set: CCDS1935

Version

ENST00000394053.2

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Transcript having exact match between ENSEMBL and HAVANA:	OTTHUMT00000252045 (version 2)

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

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Transcript: ENST00000394053.2 MTHFD2-001

Summary