Description
purinergic receptor P2X, ligand-gated ion channel, 7 [Source:HGNC Symbol;Acc:8537]
Gene Synonyms
MGC20089, P2X7
Location
Chromosome 12: 121,570,622-121,623,876 forward strand.
GRCh37:CM000674.1
About this gene
This gene has 17 transcripts (splice variants), 7 paralogues and is associated with 1 phenotype.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000546057.1 | P2RX7-008 | 2664 | 595aa | ENSP00000442349.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS9213 | K4K1I8 | NM_002562.5 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000328963.5 | P2RX7-201 | 2983 | 425aa | ENSP00000330696.5 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | K4K1I8 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000535250.1 | P2RX7-203 | 1927 | 505aa | ENSP00000442572.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | K4K1I8 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000541446.1 | P2RX7-204 | 1578 | 306aa | ENSP00000437471.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | K4K1I8 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000377162.2 | P2RX7-202 | 924 | 275aa | ENSP00000366367.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | Q99572 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000261826.6 | P2RX7-011 | 3003 | 149aa | ENSP00000261826.6 | Nonsense mediated decay | J3KN30 | - | - | |
| ENST00000537312.1 | P2RX7-004 | 2134 | 47aa | ENSP00000438586.1 | Nonsense mediated decay | F5H237 | - | - | |
| ENST00000539606.1 | P2RX7-003 | 2011 | 127aa | ENSP00000445325.1 | Nonsense mediated decay | F5H2X6 | - | - | |
| ENST00000538011.1 | P2RX7-012 | 1927 | 127aa | ENSP00000439247.1 | Nonsense mediated decay | F5H2X6 | - | - | |
| ENST00000541716.1 | P2RX7-007 | 1799 | 128aa | ENSP00000437729.1 | Nonsense mediated decay | Q99572 | - | - | |
| ENST00000541564.1 | P2RX7-010 | 1651 | 258aa | ENSP00000443640.1 | Nonsense mediated decay | F5H8E7 | - | - | |
| ENST00000535600.1 | P2RX7-005 | 1605 | 275aa | ENSP00000442470.1 | Nonsense mediated decay | Q99572 | - | - | |
| ENST00000541022.1 | P2RX7-009 | 1578 | 128aa | ENSP00000441230.1 | Nonsense mediated decay | Q99572 | - | - | |
| ENST00000535928.1 | P2RX7-015 | 546 | 47aa | ENSP00000439961.1 | Nonsense mediated decay | F5H237 | - | - | |
| ENST00000545434.1 | P2RX7-013 | 520 | 47aa | ENSP00000445564.1 | Nonsense mediated decay | F5H237 | - | - | |
| ENST00000443520.3 | P2RX7-002 | 1872 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000539695.1 | P2RX7-006 | 1832 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
