Description
thioredoxin reductase 1 [Source:HGNC Symbol;Acc:12437]
Gene Synonyms
GRIM-12, GRIM12, KDRF, TR, TR1, TRXR1, TXNR, Trxr1
Location
Chromosome 12: 104,609,557-104,744,061 forward strand.
GRCh37:CM000674.1
About this gene
This gene has 28 transcripts (splice variants) and 3 paralogues.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000525566.1 | TXNRD1-001 | 3836 | 649aa | ENSP00000434516.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS53820 | B2R5P6 B7Z904 E9PKD3 E9PKI4 E9PLT3 E9PQI3 E9PRI8 F5H780 Q16881 | NM_001093771.2 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000526691.1 | TXNRD1-002 | 3974 | 551aa | ENSP00000435929.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS53821 | B2R5P6 E9PKD3 E9PKI4 E9PLT3 E9PQI3 E9PRI8 F5H780 Q16881 | NM_003330.3 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000503506.2 | TXNRD1-003 | 3930 | 499aa | ENSP00000421934.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS53823 | B2R5P6 E9PKD3 E9PKI4 E9PLT3 E9PQI3 E9PRI8 F5H780 Q16881 | NM_182743.2 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000388854.3 | TXNRD1-203 | 3900 | 549aa | ENSP00000373506.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B2R5P6 E9PKD3 E9PKI4 E9PLT3 E9PQI3 E9PRI8 F5H780 Q16881 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000378070.4 | TXNRD1-202 | 3858 | 581aa | ENSP00000367310.4 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E7ESI6 E9PIR7 E9PKD3 E9PKI4 E9PLT3 E9PQI3 E9PRI8 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000429002.2 | TXNRD1-206 | 3828 | 647aa | ENSP00000412045.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B2R5P6 B7Z904 E9PKD3 E9PKI4 E9PLT3 E9PQI3 E9PRI8 F5H780 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000526390.1 | TXNRD1-017 | 3808 | 543aa | ENSP00000435123.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B2R5P6 E2QRB9 E9PKD3 E9PKI4 E9PLT3 E9PQI3 E9PRI8 F5H780 Q16881 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000354940.6 | TXNRD1-201 | 3790 | 497aa | ENSP00000347020.6 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B2R5P6 E9PKD3 E9PKI4 E9PLT3 E9PQI3 E9PRI8 F5H780 | NM_182742.2 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000427956.1 | TXNRD1-205 | 3701 | 612aa | ENSP00000393328.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B2R5P6 E7EW10 E9PJU2 E9PKD3 E9PKI4 E9PLT3 E9PQI3 E9PRI8 F5H780 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000397736.2 | TXNRD1-204 | 3488 | 541aa | ENSP00000380844.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B2R5P6 E2QRB9 E9PKD3 E9PKI4 E9PLT3 E9PQI3 E9PRI8 F5H780 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000540716.1 | TXNRD1-207 | 2048 | 459aa | ENSP00000442709.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PRI8 F5H780 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000529546.1 | TXNRD1-004 | 2018 | 461aa | ENSP00000434919.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS58274 | E9PRI8 F5H780 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000524698.1 | TXNRD1-006 | 1933 | 499aa | ENSP00000433425.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS53823 | B2R5P6 E9PKD3 E9PKI4 E9PLT3 E9PQI3 E9PRI8 F5H780 Q16881 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000542918.1 | TXNRD1-208 | 1933 | 547aa | ENSP00000440978.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B2R5P6 B7Z2S5 E9PKD3 E9PKI4 E9PLT3 E9PQI3 E9PRI8 F5H780 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000526950.1 | TXNRD1-009 | 1847 | 568aa | ENSP00000432812.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B2R5P6 E9PJU2 E9PKD3 E9PKI4 E9PLT3 E9PQI3 E9PRI8 F5H780 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000527335.1 | TXNRD1-014 | 786 | 175aa | ENSP00000433599.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PKD3 E9PKI4 E9PLT3 E9PQI3 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000531691.1 | TXNRD1-016 | 728 | 139aa | ENSP00000431925.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PIZ5 E9PKI4 E9PLT3 E9PQI3 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000528079.2 | TXNRD1-020 | 629 | 96aa | ENSP00000433732.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PJU2 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000529784.1 | TXNRD1-015 | 607 | 53aa | ENSP00000436229.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PQI3 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000526266.1 | TXNRD1-012 | 577 | 70aa | ENSP00000431294.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PLT3 E9PQI3 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000529751.1 | TXNRD1-021 | 557 | 44aa | ENSP00000432273.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PRI8 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000531689.1 | TXNRD1-013 | 554 | 72aa | ENSP00000433507.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PKI4 E9PLT3 E9PQI3 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000526580.1 | TXNRD1-005 | 400 | 103aa | ENSP00000433887.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PKI4 E9PLT3 E9PQI3 Q16881 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000527688.1 | TXNRD1-007 | 3858 | 482aa | ENSP00000433935.1 | Nonsense mediated decay | E9PIR7 E9PKD3 E9PKI4 E9PLT3 E9PQI3 E9PRI8 | - | - | |
| ENST00000526006.1 | TXNRD1-010 | 502 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000525265.1 | TXNRD1-019 | 572 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000526207.1 | TXNRD1-018 | 551 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000534282.1 | TXNRD1-011 | 488 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
