Description
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta [Source:HGNC Symbol;Acc:5960]
Gene Synonyms
IKK-beta, IKK2, IKKB, NFKBIKB
Location
Chromosome 8: 42,128,820-42,189,973 forward strand.
GRCh37:CM000670.1
About this gene
This gene has 30 transcripts (splice variants), 3 paralogues and is associated with 56 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000520810.1 | IKBKB-002 | 3086 | 756aa | ENSP00000430684.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS6128 | E5RGW5 O14920 | NM_001556.2 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000379708.3 | IKBKB-201 | 2778 | 533aa | ENSP00000369030.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B3KRB7 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000416505.2 | IKBKB-202 | 2501 | 697aa | ENSP00000404920.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS56535 | O14920 | NM_001242778.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000520835.1 | IKBKB-006 | 2403 | 754aa | ENSP00000430868.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS55228 | O14920 | NM_001190720.2 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000519735.1 | IKBKB-004 | 1166 | 256aa | ENSP00000430483.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | O14920 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000522147.1 | IKBKB-022 | 965 | 109aa | ENSP00000428892.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RFG5 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000518983.1 | IKBKB-019 | 447 | 76aa | ENSP00000427978.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RFT3 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000342222.2 | IKBKB-001 | 3952 | 164aa | ENSP00000339151.2 | Nonsense mediated decay | J3KNS5 | - | - | |
| ENST00000520655.1 | IKBKB-012 | 3777 | 562aa | ENSP00000428922.1 | Nonsense mediated decay | E5RGW5 G3V105 | - | - | |
| ENST00000518679.1 | IKBKB-008 | 2784 | 43aa | ENSP00000430557.1 | Nonsense mediated decay | E5RJH2 | - | - | |
| ENST00000517890.1 | IKBKB-003 | 2501 | 48aa | ENSP00000428799.1 | Nonsense mediated decay | E5RGA0 | - | - | |
| ENST00000523517.1 | IKBKB-013 | 2387 | 375aa | ENSP00000430114.1 | Nonsense mediated decay | E5RGW5 | - | - | |
| ENST00000521661.1 | IKBKB-011 | 2196 | 562aa | ENSP00000428186.1 | Nonsense mediated decay | E5RGW5 G3V105 | - | - | |
| ENST00000523105.1 | IKBKB-005 | 1966 | 48aa | ENSP00000429239.1 | Nonsense mediated decay | E5RGA0 | - | - | |
| ENST00000520320.1 | IKBKB-017 | 628 | 48aa | ENSP00000429699.1 | Nonsense mediated decay | E5RGA0 | - | - | |
| ENST00000517388.1 | IKBKB-020 | 577 | 48aa | ENSP00000429924.1 | Nonsense mediated decay | E5RGA0 | - | - | |
| ENST00000519733.1 | IKBKB-021 | 527 | 51aa | ENSP00000429319.1 | Nonsense mediated decay | E5RIW0 | - | - | |
| ENST00000517812.1 | IKBKB-018 | 523 | 48aa | ENSP00000429357.1 | Nonsense mediated decay | E5RGA0 | - | - | |
| ENST00000522785.1 | IKBKB-023 | 527 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000517502.1 | IKBKB-028 | 498 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000521225.1 | IKBKB-026 | 260 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000520201.1 | IKBKB-009 | 5002 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000519938.1 | IKBKB-014 | 2403 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000517917.1 | IKBKB-007 | 1731 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000523599.1 | IKBKB-015 | 1595 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000522103.1 | IKBKB-016 | 1575 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000518647.1 | IKBKB-010 | 1543 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000522133.1 | IKBKB-024 | 576 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000522545.1 | IKBKB-027 | 452 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000523018.1 | IKBKB-025 | 373 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
