Gene: TOP2A ENSG00000131747

Description

topoisomerase (DNA) II alpha 170kDa [Source:HGNC Symbol;Acc:11989]

Gene Synonyms

TOP2, TP2A

Location

GRCh37:CM000679.1

About this gene

This gene has 5 transcripts (splice variants), 208 orthologues, 1 paralogue and is associated with 1 phenotype.

Transcripts

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000423485.1	TOP2A-001	5758	1531aa	ENSP00000411532.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS45672	J3KTB7 J3QR57 P11388	NM_001067.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000581055.1	TOP2A-003	579	147aa	ENSP00000462908.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		J3KTB7	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000577541.1	TOP2A-006	420	27aa	ENSP00000464055.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		J3QR57	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000578412.1	TOP2A-005	882	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000577706.1	TOP2A-004	554	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Summary