Gene: TOP2B ENSG00000077097

Description

topoisomerase (DNA) II beta 180kDa [Source:HGNC Symbol;Acc:11990]

Gene Synonyms

TOPIIB, top2beta

Location

Chromosome 3: 25,639,475-25,706,398 reverse strand.

GRCh37:CM000665.1

About this gene

This gene has 9 transcripts (splice variants), 1 paralogue and is associated with 1 phenotype.

Transcripts

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Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000435706.2	TOP2B-001	5389	1621aa	ENSP00000396704.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS46776	B4DLV2 E9PCY5 Q02880 Q6LC06 Q8WTY5	NM_001068.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000264331.4	TOP2B-201	5189	1626aa	ENSP00000264331.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B4DLV2 Q02880 Q6LBI8 Q6LC06 Q8WTY5	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000424225.1	TOP2B-002	3525	1150aa	ENSP00000391112.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E9PCY5 Q6LC06	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000542520.1	TOP2B-203	2061	478aa	ENSP00000446023.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B4DLV2	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000540199.1	TOP2B-202	1897	478aa	ENSP00000437352.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B4DLV2	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000413971.1	TOP2B-005	2049	70aa	ENSP00000388216.1	Nonsense mediated decay		H7BZ82	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000475717.1	TOP2B-008	540	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000491510.1	TOP2B-006	584	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000470132.1	TOP2B-007	451	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Gene: TOP2B ENSG00000077097

Summary