Description
protein tyrosine phosphatase, non-receptor type 6 [Source:HGNC Symbol;Acc:9658]
Gene Synonyms
HCP, HCPH, HPTP1C, PTP-1C, PTP1C, SH-PTP1, SHP-1, SHP-1L, SHP1
Location
Chromosome 12: 7,055,631-7,070,479 forward strand.
GRCh37:CM000674.1
View alleles of this gene on alternative sequences
About this gene
This gene has 24 transcripts (splice variants), 1 gene allele, 13 paralogues and is associated with 48 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000456013.1 | PTPN6-202 | 2389 | 624aa | ENSP00000391592.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS44821 | F5H0N8 P29350 | NM_080549.3 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000318974.9 | PTPN6-008 | 2245 | 595aa | ENSP00000326010.9 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS44820 | F5H0N8 P29350 | NM_002831.5 | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000399448.1 | PTPN6-001 | 2159 | 597aa | ENSP00000382376.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS41744 | P29350 Q53XS4 | NM_080548.4 | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000447931.2 | PTPN6-201 | 1971 | 556aa | ENSP00000415979.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | P29350 | - | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, | |
| ENST00000543115.1 | PTPN6-018 | 650 | 130aa | ENSP00000443393.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F5H5H9 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000541698.1 | PTPN6-023 | 592 | 150aa | ENSP00000445646.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F5H1Z8 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000538715.1 | PTPN6-014 | 579 | 165aa | ENSP00000438740.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F5H0N8 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000542462.1 | PTPN6-021 | 570 | 144aa | ENSP00000440114.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F5GY79 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000545153.1 | PTPN6-012 | 959 | 72aa | ENSP00000476175.1 | Nonsense mediated decay | U3KQS1 | - | - | |
| ENST00000542848.1 | PTPN6-019 | 656 | 58aa | ENSP00000444805.1 | Nonsense mediated decay | F5H4Z1 | - | - | |
| ENST00000536013.1 | PTPN6-013 | 602 | 56aa | ENSP00000446345.1 | Nonsense mediated decay | F5H1V7 | - | - | |
| ENST00000535462.1 | PTPN6-016 | 543 | 60aa | ENSP00000441044.1 | Nonsense mediated decay | F5GXD4 | - | - | |
| ENST00000539029.1 | PTPN6-004 | 705 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000537533.1 | PTPN6-005 | 673 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000542277.1 | PTPN6-007 | 664 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000540740.1 | PTPN6-011 | 592 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000543120.1 | PTPN6-010 | 564 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000534900.1 | PTPN6-025 | 538 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000416215.2 | PTPN6-003 | 2412 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000543744.1 | PTPN6-002 | 2043 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000539365.1 | PTPN6-022 | 907 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000542761.1 | PTPN6-006 | 795 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000538318.1 | PTPN6-024 | 759 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000536521.1 | PTPN6-015 | 513 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
