Description
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:7728]
Gene Synonyms
KIAA0439, NEDD4-2, NEDD4.2, NEDL3, RSP5, hNEDD4-2
Location
Chromosome 18: 55,711,599-56,068,772 forward strand.
GRCh37:CM000680.1
About this gene
This gene has 37 transcripts (splice variants), 11 paralogues and is associated with 3 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000400345.3 | NEDD4L-001 | 3647 | 975aa | ENSP00000383199.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS45872 | K7EN51 K7ENS6 Q96PU5 | NM_001144967.2 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000456986.1 | NEDD4L-202 | 8436 | 854aa | ENSP00000411947.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS45875 | K7EN51 K7ENS6 Q96PU5 | NM_001144964.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000256832.7 | NEDD4L-201 | 8416 | 835aa | ENSP00000256832.7 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F5H602 K7EN51 K7ENS6 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000382850.4 | NEDD4L-002 | 8251 | 955aa | ENSP00000372301.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS45873 | K7EN51 K7ENS6 Q96PU5 | NM_015277.5 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000456173.2 | NEDD4L-013 | 4978 | 834aa | ENSP00000405440.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS45876 | K7EN51 K7ENS6 Q96PU5 | NM_001144970.2 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000357895.5 | NEDD4L-003 | 3543 | 967aa | ENSP00000350569.4 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS45874 | K7EN51 K7ENS6 Q96PU5 | NM_001144968.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000435432.2 | NEDD4L-017 | 3417 | 834aa | ENSP00000393395.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS45876 | K7EN51 K7ENS6 Q96PU5 | NM_001144971.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000586263.1 | NEDD4L-004 | 3347 | 947aa | ENSP00000468546.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS59323 | K7EN51 K7ENS6 Q96PU5 | NM_001144969.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000431212.2 | NEDD4L-014 | 3338 | 854aa | ENSP00000389406.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS45875 | K7EN51 K7ENS6 Q96PU5 | NM_001144966.2 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000356462.6 | NEDD4L-005 | 3335 | 911aa | ENSP00000348847.5 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS58632 | K7EN51 K7ENS6 Q96PU5 | NM_001243960.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000256830.9 | NEDD4L-037 | 2920 | 871aa | ENSP00000256830.8 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | K7EN51 K7ENS6 Q96PU5 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000587881.1 | NEDD4L-030 | 1984 | 639aa | ENSP00000468332.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | K7ERN1 Q5XLQ3 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000589054.1 | NEDD4L-022 | 1033 | 106aa | ENSP00000465669.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | K7EKL1 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000586268.1 | NEDD4L-024 | 830 | 150aa | ENSP00000467072.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | K7EN51 K7ENS6 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000587190.1 | NEDD4L-016 | 553 | 15aa | ENSP00000467768.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000588494.1 | NEDD4L-019 | 505 | 35aa | ENSP00000466789.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | K7EN51 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000592846.1 | NEDD4L-020 | 484 | 10aa | ENSP00000466776.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000588516.1 | NEDD4L-009 | 1304 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000587547.1 | NEDD4L-011 | 889 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000587634.1 | NEDD4L-023 | 628 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000588066.1 | NEDD4L-018 | 579 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000592601.1 | NEDD4L-025 | 551 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000585970.1 | NEDD4L-041 | 487 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000587246.1 | NEDD4L-032 | 406 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000585323.1 | NEDD4L-015 | 381 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000585363.1 | NEDD4L-008 | 241 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000591989.1 | NEDD4L-039 | 233 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000585594.1 | NEDD4L-010 | 220 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000590694.1 | NEDD4L-007 | 165 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000591579.1 | NEDD4L-006 | 144 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000590506.1 | NEDD4L-035 | 2743 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000588712.1 | NEDD4L-034 | 2066 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000590638.1 | NEDD4L-028 | 862 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000589167.1 | NEDD4L-027 | 754 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000590248.1 | NEDD4L-036 | 730 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000590020.1 | NEDD4L-026 | 710 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000592097.1 | NEDD4L-033 | 582 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
