Description
Rap guanine nucleotide exchange factor (GEF) 4 [Source:HGNC Symbol;Acc:16626]
Gene Synonyms
2, CAMP-GEFII, CGEF2, EPAC, EPAC 2, EPAC2, Nbla00496, cAMP-GEFII
Location
Chromosome 2: 173,600,002-173,917,621 forward strand.
GRCh37:CM000664.1
About this gene
This gene has 17 transcripts (splice variants) and 9 paralogues.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000397081.3 | RAPGEF4-001 | 4299 | 1011aa | ENSP00000380271.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS42775 | B7Z278 B7Z283 Q53QY2 Q53TH3 Q8WZA2 | NM_007023.3 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000264111.6 | RAPGEF4-201 | 4338 | 1010aa | ENSP00000264111.6 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B7Z278 E7EVE5 Q53QY2 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000397087.3 | RAPGEF4-004 | 4120 | 867aa | ENSP00000380276.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS42776 | B7Z278 B7Z283 Q53QY2 Q8WZA2 | NM_001282901.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000409036.1 | RAPGEF4-011 | 3975 | 943aa | ENSP00000387104.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PB94 Q53QY2 Q53TH3 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000540783.1 | RAPGEF4-205 | 3229 | 858aa | ENSP00000440250.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS63060 | B7Z278 B7Z283 Q53QY2 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000539331.1 | RAPGEF4-204 | 2961 | 858aa | ENSP00000437384.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS63060 | B7Z278 B7Z283 Q53QY2 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000538974.1 | RAPGEF4-203 | 2930 | 840aa | ENSP00000440135.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS63061 | B7Z278 B7Z3T6 | NM_001282900.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000535187.1 | RAPGEF4-202 | 2722 | 791aa | ENSP00000438011.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B7Z278 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000397085.3 | RAPGEF4-003 | 649 | 187aa | ENSP00000380274.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | H7BYQ0 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000473043.1 | RAPGEF4-010 | 1075 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000464976.1 | RAPGEF4-009 | 980 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000473003.1 | RAPGEF4-013 | 593 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000459852.1 | RAPGEF4-008 | 560 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000484331.1 | RAPGEF4-012 | 547 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000466030.1 | RAPGEF4-006 | 493 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000484645.1 | RAPGEF4-002 | 842 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000473182.2 | RAPGEF4-007 | 599 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
