Gene: GPC3 ENSG00000147257

Description

glypican 3 [Source:HGNC Symbol;Acc:4451]

Gene Synonyms

DGSX, GTR2-2, MXR7, OCI-5, OCI5, SDYS, SGB, SGBS, SGBS1

Location

GRCh37:CM000685.1

About this gene

This gene has 4 transcripts (splice variants), 5 paralogues and is associated with 56 phenotypes.

Transcripts

Transcript ID	Name	bp	Protein	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000394299.2	GPC3-201	2379	603aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS55496	P51654	NM_001164617.1	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000370818.3	GPC3-001	2568	580aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS14638	I6QTG3 P51654	NM_004484.3	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000543339.1	GPC3-202	1581	526aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS55495	P51654	NM_001164619.1	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000406757.2	GPC3-002	836	256aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,

Summary

Name

GPC3 (HGNC Symbol)

UniProtKB

This gene has proteins that correspond to the following UniProtKB identifiers: P51654

CCDS

This gene is a member of the Human CCDS set: CCDS14638.1, CCDS55495.1, CCDS55496.1

LRG

LRG_505 provides a stable genomic reference framework for describing sequence variants for this gene

Ensembl version

ENSG00000147257.9

Other assemblies

There is no ungapped mapping of this gene onto the GRCh38 assembly.

Gene type

Protein coding

Annotation method

Annotation for this gene includes both automatic annotation from Ensembl and Havana manual curation, see article.

Alternative genes

This gene corresponds to the following database identifiers:

Havana gene:	OTTHUMG00000022448 (version 1)

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