Gene: PROS1 ENSG00000184500

Description

protein S (alpha) [Source:HGNC Symbol;Acc:9456]

Gene Synonyms

PROS, PS21, PS22, PS23, PS24, PS25, PSA, THPH5, THPH6

Location

Chromosome 3: 93,591,881-93,692,910 reverse strand.

GRCh37:CM000665.1

About this gene

This gene has 5 transcripts (splice variants), 2 paralogues and is associated with 4 phenotypes.

Transcripts

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Transcript ID	Name	bp	Protein	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000394236.3	PROS1-001	3556	676aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS2923	B4E1L6 C9K0R0 G5E9F8 P07225 Q06F35 Q6J1N0 Q8IXD2 Q8IXD4 Q8IXD5	NM_000313.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000407433.1	PROS1-002	3335	545aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B4E1L6 C9K0R0 G5E9F8 Q06F35 Q8IXD2 Q8IXD4	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000348974.4	PROS1-003	806	231aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		C9K0R0 H7BXT0 Q6J1N0 Q8IXD5	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000472684.1	PROS1-004	562	56aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		C9K0R0	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000488658.1	PROS1-005	643	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Summary

Name

PROS1 (HGNC Symbol)

UniProtKB

This gene has proteins that correspond to the following UniProtKB identifiers: P07225

CCDS

This gene is a member of the Human CCDS set: CCDS2923.1

Ensembl version

ENSG00000184500.10

Other assemblies

This gene maps to 93,873,037-93,974,066 in GRCh38 coordinates.

Gene type

Protein coding

Annotation method

Annotation for this gene includes both automatic annotation from Ensembl and Havana manual curation, see article.

Alternative genes

This gene corresponds to the following database identifiers:

Havana gene:	OTTHUMG00000150354 (version 2)

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Gene: PROS1 ENSG00000184500

Summary