Gene: AKT2 ENSG00000105221

Description

v-akt murine thymoma viral oncogene homolog 2 [Source:HGNC Symbol;Acc:392]

Gene Synonyms

HIHGHH, PKBB, PKBBETA, PRKBB, RAC-BETA

Location

Chromosome 19: 40,736,224-40,791,443 reverse strand.

GRCh37:CM000681.1

About this gene

This gene has 42 transcripts (splice variants), 15 paralogues and is associated with 63 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000392038.2	AKT2-001	5300	481aa	ENSP00000375892.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS12552	A8MX96 B3KP61 B4DG79 C9J258 C9JC83 C9JHS6 C9JIF6 C9JIJ1 E7EVP8 J3KRI8 J3KSY8 J3QL45 J3QLS6 J3QQM6 M0QZK3 P31751 Q05BV0	NM_001626.4	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000579047.1	AKT2-025	2029	450aa	ENSP00000471369.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		J3QL45 M0R0P9	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000424901.1	AKT2-201	1497	481aa	ENSP00000399532.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS12552	A8MX96 B3KP61 B4DG79 C9J258 C9JC83 C9JHS6 C9JIF6 C9JIJ1 E7EVP8 J3KRI8 J3KSY8 J3QL45 J3QLS6 J3QQM6 M0QZK3 P31751 Q05BV0	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000311278.6	AKT2-027	1393	438aa	ENSP00000309428.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A8MX96 C9J258 C9JC83 C9JHS6 C9JIF6 C9JIJ1 E7EVP8 J3KRI8 J3KSY8 J3QL45 J3QLS6 J3QQM6 M0QZK3 Q0VAN0	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000441941.2	AKT2-012	974	184aa	ENSP00000396968.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A8MX96 C9J258 C9JC83 C9JHS6 C9JIF6 C9JIJ1 E7EVP8 J3KRI8 J3KSY8 J3QLS6 J3QQM6 M0QZK3	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000416362.1	AKT2-010	974	132aa	ENSP00000407999.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A8MX96 C9J258 C9JC83 C9JIF6 C9JIJ1 J3KRI8 J3KSY8 J3QQM6	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000416994.2	AKT2-008	904	95aa	ENSP00000392458.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		C9J258 C9JIF6	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000578615.1	AKT2-035	877	292aa	ENSP00000463262.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		J3QKW1	-	5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete,
ENST00000423127.1	AKT2-007	798	119aa	ENSP00000403842.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		C9J258 C9JC83 C9JIF6 C9JIJ1 J3KSY8 J3QQM6	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000392037.1	AKT2-014	681	133aa	ENSP00000375891.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A8MX96 C9J258 C9JC83 C9JIF6 C9JIJ1 J3KRI8 J3KSY8 J3QQM6	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000486368.2	AKT2-033	606	157aa	ENSP00000463686.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A8MX96 C9J258 C9JC83 C9JIF6 C9JIJ1 E7EVP8 J3KRI8 J3KSY8 J3QLS6 J3QQM6 M0QZK3	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000596634.1	AKT2-045	583	151aa	ENSP00000470604.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A8MX96 C9J258 C9JC83 C9JIF6 C9JIJ1 E7EVP8 J3KRI8 J3KSY8 J3QQM6 M0QZK3	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000456441.1	AKT2-006	582	107aa	ENSP00000396532.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		C9J258 C9JC83 C9JIF6 J3KSY8 J3QQM6	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000452077.1	AKT2-005	577	134aa	ENSP00000404083.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A8MX96 C9J258 C9JC83 C9JIF6 C9JIJ1 E7EVP8 J3KRI8 J3KSY8 J3QQM6	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000583859.1	AKT2-030	567	99aa	ENSP00000462715.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		C9J258 C9JIF6 J3KSY8 J3QQM6	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000578123.1	AKT2-029	564	130aa	ENSP00000462022.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		C9J258 C9JC83 C9JIF6 C9JIJ1 J3KRI8 J3KSY8 J3QQM6	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000427375.1	AKT2-011	554	67aa	ENSP00000403890.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		C9JIF6	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000358335.5	AKT2-042	546	125aa	ENSP00000351095.5	Gene/transcipt that contains an open reading frame (ORF).Protein coding		F8W8B1	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000580747.1	AKT2-032	528	96aa	ENSP00000463806.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		C9J258 C9JIF6 J3QQM6	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000476247.2	AKT2-041	488	106aa	ENSP00000463368.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		J3QL45	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000497948.1	AKT2-021	456	117aa	ENSP00000472382.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000578310.1	AKT2-036	158	53aa	ENSP00000462919.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete,
ENST00000391844.4	AKT2-026	1795	69aa	ENSP00000375719.4	Nonsense mediated decay		J3KT31	-	-
ENST00000584288.1	AKT2-024	1706	69aa	ENSP00000462469.1	Nonsense mediated decay		J3KT31	-	-
ENST00000492463.2	AKT2-013	737	69aa	ENSP00000462776.1	Nonsense mediated decay		J3KT31	-	-
ENST00000489375.1	AKT2-019	734	56aa	ENSP00000470822.1	Nonsense mediated decay		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000491778.2	AKT2-034	573	51aa	ENSP00000463086.1	Nonsense mediated decay		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000601166.1	AKT2-044	554	129aa	ENSP00000472371.1	Nonsense mediated decay		M0R275	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000581582.1	AKT2-031	655	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000391845.2	AKT2-017	636	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000498350.1	AKT2-009	562	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000480878.2	AKT2-037	508	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000486647.1	AKT2-023	457	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000483166.1	AKT2-003	4454	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000578975.1	AKT2-043	3337	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000476266.1	AKT2-002	3309	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000537834.1	AKT2-016	1402	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000496089.2	AKT2-022	982	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000487537.2	AKT2-015	954	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000580878.1	AKT2-038	709	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000579345.1	AKT2-039	561	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000578282.1	AKT2-040	305	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Gene: AKT2 ENSG00000105221

Summary