Description
checkpoint kinase 2 [Source:HGNC Symbol;Acc:16627]
Gene Synonyms
CDS1, CHK2, HuCds1, LFS2, PP1425, RAD53, bA444G7, hCds1
Location
Chromosome 22: 29,083,731-29,138,410 reverse strand.
GRCh37:CM000684.1
About this gene
This gene has 27 transcripts (splice variants) and is associated with 82 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000382580.2 | CHEK2-003 | 1971 | 586aa | ENSP00000372023.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS33629 | B7ZBF2 O96017 | NM_001005735.1 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000544772.1 | CHEK2-205 | 2560 | 322aa | ENSP00000442458.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS58798 | B7ZBF2 O96017 | NM_001257387.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000405598.1 | CHEK2-005 | 1959 | 543aa | ENSP00000386087.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS13843 | B7ZBF2 O96017 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000328354.6 | CHEK2-002 | 1867 | 543aa | ENSP00000329178.6 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS13843 | B7ZBF2 O96017 | NM_007194.3 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000382566.1 | CHEK2-203 | 1796 | 289aa | ENSP00000372007.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | O96017 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000404276.1 | CHEK2-006 | 1785 | 543aa | ENSP00000385747.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS13843 | B7ZBF2 O96017 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000348295.3 | CHEK2-201 | 1771 | 514aa | ENSP00000329012.5 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS13844 | O96017 | NM_145862.2 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000382578.1 | CHEK2-204 | 1585 | 452aa | ENSP00000372021.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B7ZBF2 O96017 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000402731.1 | CHEK2-022 | 1545 | 514aa | ENSP00000384835.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS13844 | O96017 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000403642.1 | CHEK2-021 | 1359 | 452aa | ENSP00000384919.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B7ZBF2 O96017 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000434810.1 | CHEK2-018 | 984 | 276aa | ENSP00000416721.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000439200.1 | CHEK2-013 | 906 | 295aa | ENSP00000408065.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B7ZBF7 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000447421.1 | CHEK2-010 | 903 | 299aa | ENSP00000397478.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B7ZBF6 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000425190.2 | CHEK2-011 | 752 | 121aa | ENSP00000390244.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B7ZBF2 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000382565.1 | CHEK2-202 | 718 | 163aa | ENSP00000372006.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | C9JFD7 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000398017.2 | CHEK2-012 | 713 | 172aa | ENSP00000381099.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B7ZBF8 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000456369.1 | CHEK2-019 | 588 | 144aa | ENSP00000394430.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000416671.1 | CHEK2-001 | 2560 | 207aa | ENSP00000402225.1 | Nonsense mediated decay | E7EPP1 | - | - | |
| ENST00000433728.1 | CHEK2-023 | 1580 | 289aa | ENSP00000404400.1 | Nonsense mediated decay | O96017 | - | - | |
| ENST00000417588.1 | CHEK2-009 | 1551 | 203aa | ENSP00000412901.1 | Nonsense mediated decay | H7C0V7 O96017 | - | - | |
| ENST00000448511.1 | CHEK2-008 | 1532 | 165aa | ENSP00000404567.1 | Nonsense mediated decay | O96017 | - | - | |
| ENST00000433028.2 | CHEK2-004 | 1349 | 161aa | ENSP00000403659.1 | Nonsense mediated decay | F8WCV2 | - | - | |
| ENST00000454252.1 | CHEK2-014 | 722 | 45aa | ENSP00000387451.1 | Nonsense mediated decay | H7BZ30 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000439346.1 | CHEK2-015 | 553 | 57aa | ENSP00000396903.1 | Nonsense mediated decay | H7C0V7 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000464581.1 | CHEK2-017 | 425 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000491919.1 | CHEK2-016 | 609 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000472807.1 | CHEK2-020 | 514 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
