Description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 [Source:HGNC Symbol;Acc:8874]
Gene Synonyms
IPFK2, PFK2
Location
Chromosome 10: 6,186,881-6,277,495 forward strand.
GRCh37:CM000672.1
About this gene
This gene has 17 transcripts (splice variants) and 3 paralogues.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000379775.4 | PFKFB3-002 | 4483 | 520aa | ENSP00000369100.4 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS7078 | Q16875 Q5VX18 Q9UBT0 | NM_004566.3 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000379789.4 | PFKFB3-001 | 4157 | 500aa | ENSP00000369115.4 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS44353 | Q16875 | NM_001145443.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000536985.1 | PFKFB3-202 | 3922 | 184aa | ENSP00000443319.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F5H5L1 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000379785.1 | PFKFB3-010 | 2181 | 526aa | ENSP00000369111.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | Q5VX20 Q5W015 Q9BQU2 Q9UBT0 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000540253.1 | PFKFB3-203 | 2094 | 534aa | ENSP00000446384.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS60479 | B7Z955 | NM_001282630.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000317350.4 | PFKFB3-015 | 1999 | 513aa | ENSP00000369105.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | Q5W015 Q9UBT0 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000379782.3 | PFKFB3-201 | 1965 | 526aa | ENSP00000369108.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | Q5VX20 Q5W015 Q9BQU2 Q9UBT0 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000360521.2 | PFKFB3-006 | 1964 | 514aa | ENSP00000353712.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | Q16875 Q5W015 Q9UBT0 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000450232.1 | PFKFB3-013 | 595 | 143aa | ENSP00000390285.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | Q9BQU1 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000414237.1 | PFKFB3-005 | 513 | 92aa | ENSP00000416677.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | Q9H178 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000441697.1 | PFKFB3-011 | 244 | 31aa | ENSP00000404995.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | Q9BQU1 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000467491.1 | PFKFB3-008 | 2131 | 455aa | ENSP00000434628.1 | Nonsense mediated decay | F2Z2I2 Q9UBT0 | - | - | |
| ENST00000461744.1 | PFKFB3-012 | 2098 | 455aa | ENSP00000433771.1 | Nonsense mediated decay | F2Z2I2 Q9UBT0 | - | - | |
| ENST00000490474.1 | PFKFB3-007 | 2086 | 455aa | ENSP00000436885.1 | Nonsense mediated decay | F2Z2I2 Q9UBT0 | - | - | |
| ENST00000477914.1 | PFKFB3-009 | 2063 | 455aa | ENSP00000432356.1 | Nonsense mediated decay | F2Z2I2 Q9UBT0 | - | - | |
| ENST00000475881.1 | PFKFB3-004 | 536 | 61aa | ENSP00000434342.1 | Nonsense mediated decay | H0YDV0 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000487989.1 | PFKFB3-014 | 661 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
