Gene: PRNP ENSG00000171867

Description

prion protein [Source:HGNC Symbol;Acc:9449]

Gene Synonyms

ASCR, AltPrP, CD230, CJD, GSS, KURU, PRIP, PRP, PrP, PrP27-30, PrP33-35C, PrPc, p27-30

Location

GRCh37:CM000682.1

About this gene

This gene has 4 transcripts (splice variants) and is associated with 13 phenotypes.

Transcripts

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000379440.4	PRNP-002	2657	253aa	ENSP00000368752.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS13080	A2A2V1 O75942 P04156 Q53YK7 Q6SES1 Q86XR1	NM_183079.2	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000430350.2	PRNP-003	2539	253aa	ENSP00000399376.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS13080	A2A2V1 O75942 P04156 Q53YK7 Q6SES1 Q86XR1	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000457586.1	PRNP-001	855	217aa	ENSP00000415284.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B2NI04	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000424424.1	PRNP-004	806	249aa	ENSP00000411599.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A2A2V1	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,

Summary