Gene: IL6R ENSG00000160712

Description

interleukin 6 receptor [Source:HGNC Symbol;Acc:6019]

Gene Synonyms

CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80

Location

Chromosome 1: 154,377,669-154,441,926 forward strand.

GRCh37:CM000663.1

About this gene

This gene has 7 transcripts (splice variants), 4 paralogues and is associated with 2 phenotypes.

Transcripts

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Transcript ID	Name	bp	Protein	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000368485.3	IL6R-001	5914	468aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS1067	A0N0L5 P08887	NM_000565.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000344086.4	IL6R-003	3217	365aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS1068	P08887	NM_181359.2	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000476006.1	IL6R-002	881	294aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete,
ENST00000515190.1	IL6R-007	570	190aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete,
ENST00000512471.1	IL6R-004	527	170aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		D6R9R8	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000507256.1	IL6R-005	539	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000502679.1	IL6R-006	588	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Summary

Name

IL6R (HGNC Symbol)

UniProtKB

This gene has proteins that correspond to the following UniProtKB identifiers: P08887

CCDS

This gene is a member of the Human CCDS set: CCDS1067.1, CCDS1068.1

Ensembl version

ENSG00000160712.8

Other assemblies

This gene maps to 154,405,193-154,469,450 in GRCh38 coordinates.

Gene type

Protein coding

Annotation method

Annotation for this gene includes both automatic annotation from Ensembl and Havana manual curation, see article.

Alternative genes

This gene corresponds to the following database identifiers:

Havana gene:	OTTHUMG00000036073 (version 2)

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Gene: IL6R ENSG00000160712

Summary