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Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: MAP3K3 ENSG00000198909

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Description

mitogen-activated protein kinase kinase kinase 3 [Source:HGNC Symbol;Acc:6855]

Gene Synonyms

MAPKKK3, MEKK3

Location

Chromosome 17: 61,699,775-61,773,663 forward strand.

GRCh37:CM000679.1

About this gene

This gene has 11 transcripts (splice variants) and 7 paralogues.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000361357.3	MAP3K3-001	4818	657aa	ENSP00000354927.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS32701	Q7Z4E6 Q99759	NM_203351.1	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000361733.3	MAP3K3-004	3529	626aa	ENSP00000354485.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS32702	Q7Z4E6 Q96HN9 Q99759	NM_002401.3	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000579585.1	MAP3K3-007	3352	657aa	ENSP00000461988.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS32701	Q7Z4E6 Q99759	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000584573.1	MAP3K3-002	2480	653aa	ENSP00000464130.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		J3QRB6 Q7Z4E6	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000577395.1	MAP3K3-005	2016	622aa	ENSP00000462086.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		J3KRN4 Q7Z4E6	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000577597.1	MAP3K3-006	2024	56aa	ENSP00000462917.1	Nonsense mediated decay		J3KTC4	-	-
ENST00000585302.1	MAP3K3-008	678	31aa	ENSP00000464532.1	Nonsense mediated decay		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000581732.1	MAP3K3-010	580	42aa	ENSP00000464482.1	Nonsense mediated decay		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000577784.1	MAP3K3-011	565	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000577839.1	MAP3K3-012	594	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000578622.1	MAP3K3-009	560	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Summary

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