Description
catechol-O-methyltransferase [Source:HGNC Symbol;Acc:2228]
Location
Chromosome 22: 19,929,130-19,957,498 forward strand.
GRCh37:CM000684.1
About this gene
This gene has 11 transcripts (splice variants), 1 paralogue and is associated with 3 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000361682.6 | COMT-011 | 2437 | 271aa | ENSP00000354511.6 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS13770 | E7EMS6 F2WW53 P21964 Q7KZP0 | NM_000754.3 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000403184.1 | COMT-004 | 2217 | 235aa | ENSP00000383966.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E7EUU8 F2WW53 Q7KZP0 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000449653.1 | COMT-201 | 2035 | 221aa | ENSP00000416778.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS46663 | F2WW53 P21964 | NM_007310.2 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000403710.1 | COMT-002 | 1548 | 271aa | ENSP00000385917.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS13770 | E7EMS6 F2WW53 P21964 Q7KZP0 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000407537.1 | COMT-003 | 1457 | 221aa | ENSP00000384654.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS46663 | F2WW53 P21964 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000406520.3 | COMT-001 | 1339 | 271aa | ENSP00000385150.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS13770 | E7EMS6 F2WW53 P21964 Q7KZP0 | NM_001135162.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000412786.1 | COMT-005 | 871 | 223aa | ENSP00000403958.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E7EMS6 F2WW53 Q7KZP0 | NM_001135161.1 | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000428707.1 | COMT-008 | 724 | 152aa | ENSP00000387695.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000207636.5 | COMT-007 | 1319 | 199aa | ENSP00000207636.5 | Nonsense mediated decay | F2WW53 F8WBW9 Q7KZP0 | - | - | |
| ENST00000493893.1 | COMT-010 | 354 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000467943.1 | COMT-009 | 546 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
