Gene: CYP2D6 ENSG00000100197

Description

cytochrome P450, family 2, subfamily D, polypeptide 6 [Source:HGNC Symbol;Acc:2625]

Gene Synonyms

CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1

Location

GRCh37:CM000684.1

View alleles of this gene on alternative sequences

About this gene

This gene has 5 transcripts (splice variants), 1 gene allele, 15 paralogues and is associated with 1 phenotype.

Transcripts

Transcript ID	Name	bp	Protein	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000360608.5	CYP2D6-001	1684	497aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS46721	Q007T9 Q6NWU0	NM_000106.5	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000389970.3	CYP2D6-201	1657	497aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E7ENE7 Q007T9	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000359033.4	CYP2D6-002	1433	446aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS33657	P10635 Q007T9	NM_001025161.2	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000360124.5	CYP2D6-003	1187	180aa	Nonsense mediated decay		H7BY38	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000488442.1	CYP2D6-004	2257	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Summary

Name

CYP2D6 (HGNC Symbol)

UniProtKB

This gene has proteins that correspond to the following UniProtKB identifiers: P10635

CCDS

This gene is a member of the Human CCDS set: CCDS33657.1, CCDS46721.1

Ensembl version

ENSG00000100197.16

Other assemblies

This gene maps to 42,126,499-42,130,906 in GRCh38 coordinates.

Gene type

Protein coding

Annotation method

Annotation for this gene includes both automatic annotation from Ensembl and Havana manual curation, see article.

Alternative genes

This gene corresponds to the following database identifiers:

Havana gene:	OTTHUMG00000150918 (version 2)

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