Description
pleckstrin homology domain containing, family G (with RhoGef domain) member 4 [Source:HGNC Symbol;Acc:24501]
Gene Synonyms
ARHGEF44, DKFZP434I216, PRTPHN1, SCA4
Location
Chromosome 16: 67,311,413-67,323,402 forward strand.
GRCh37:CM000678.1
About this gene
This gene has 15 transcripts (splice variants), 9 paralogues and is associated with 1 phenotype.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000360461.5 | PLEKHG4-002 | 6782 | 1191aa | ENSP00000353646.5 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS32466 | C5IFI8 H3BME5 H3BPQ5 H3BQE6 H3BQP9 H3BSU4 Q58EX7 | NM_015432.3 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000379344.3 | PLEKHG4-005 | 4513 | 1191aa | ENSP00000368649.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS32466 | C5IFI8 H3BME5 H3BPQ5 H3BQE6 H3BQP9 H3BSU4 Q58EX7 | NM_001129729.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000450733.1 | PLEKHG4-006 | 4480 | 1110aa | ENSP00000398030.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS45512 | C5IFI8 H3BME5 H3BPQ5 H3BQE6 H3BQP9 H3BSU4 Q58EX7 | NM_001129731.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000427155.2 | PLEKHG4-004 | 4455 | 1191aa | ENSP00000401118.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS32466 | C5IFI8 H3BME5 H3BPQ5 H3BQE6 H3BQP9 H3BSU4 Q58EX7 | NM_001129728.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000562144.1 | PLEKHG4-011 | 574 | 76aa | ENSP00000454348.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | H3BME5 H3BPQ5 H3BSU4 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000565899.1 | PLEKHG4-012 | 560 | 73aa | ENSP00000455423.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | H3BPQ5 H3BSU4 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000565773.1 | PLEKHG4-013 | 542 | 108aa | ENSP00000455876.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | C5IFI8 H3BME5 H3BPQ5 H3BQE6 H3BQP9 H3BSU4 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000568621.1 | PLEKHG4-019 | 514 | 36aa | ENSP00000456873.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | H3BSU4 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000562744.1 | PLEKHG4-017 | 491 | 64aa | ENSP00000455622.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | H3BQ60 H3BSU4 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000569875.1 | PLEKHG4-016 | 489 | 125aa | ENSP00000464631.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | J3QSC9 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000567938.1 | PLEKHG4-018 | 466 | 77aa | ENSP00000455740.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | H3BME5 H3BPQ5 H3BQE6 H3BSU4 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000563969.1 | PLEKHG4-001 | 6949 | 193aa | ENSP00000457086.1 | Nonsense mediated decay | C5IFI8 H3BME5 H3BPQ5 H3BQE6 H3BQP9 H3BSU4 Q58EX7 | - | - | |
| ENST00000393966.1 | PLEKHG4-007 | 2182 | 193aa | ENSP00000462601.1 | Nonsense mediated decay | C5IFI8 H3BME5 H3BPQ5 H3BQE6 H3BQP9 H3BSU4 Q58EX7 | - | - | |
| ENST00000567136.1 | PLEKHG4-020 | 698 | 106aa | ENSP00000455228.1 | Nonsense mediated decay | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000562289.1 | PLEKHG4-014 | 1298 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
