Description
DNA (cytosine-5-)-methyltransferase 1 [Source:HGNC Symbol;Acc:2976]
Gene Synonyms
ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT
Location
Chromosome 19: 10,244,021-10,341,962 reverse strand.
GRCh37:CM000681.1
About this gene
This gene has 29 transcripts (splice variants) and is associated with 4 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000359526.4 | DNMT1-002 | 5206 | 1632aa | ENSP00000352516.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS45958 | B3KVA0 I6L9H2 K7EKC3 K7ELB1 P26358 | NM_001130823.1 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000340748.4 | DNMT1-001 | 5408 | 1616aa | ENSP00000345739.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS12228 | B3KVA0 K7EKC3 K7ENQ6 K7ERQ1 P26358 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000540357.1 | DNMT1-201 | 5360 | 1619aa | ENSP00000440457.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F5GX68 K7EKC3 K7ENQ6 K7ERQ1 Q59FP7 | NM_001379.2 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000588118.1 | DNMT1-009 | 973 | 255aa | ENSP00000465223.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | K7EJL0 K7EKC3 K7ERQ1 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000588952.1 | DNMT1-012 | 841 | 119aa | ENSP00000467050.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | K7EKC3 K7ENQ6 K7ERQ1 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000592342.1 | DNMT1-011 | 636 | 94aa | ENSP00000465993.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | K7EKC3 K7ELB1 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000592054.1 | DNMT1-013 | 591 | 71aa | ENSP00000468359.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | K7EKC3 K7ERQ1 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000586800.1 | DNMT1-010 | 583 | 25aa | ENSP00000465555.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | K7EKC3 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000590619.1 | DNMT1-005 | 231 | 77aa | ENSP00000468062.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete, | |
| ENST00000592705.1 | DNMT1-006 | 5215 | 89aa | ENSP00000466657.1 | Nonsense mediated decay | K7EMU8 | - | - | |
| ENST00000588913.1 | DNMT1-008 | 1775 | 389aa | ENSP00000467125.1 | Nonsense mediated decay | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000586988.1 | DNMT1-015 | 711 | 40aa | ENSP00000464958.1 | Nonsense mediated decay | K7EIZ6 | - | - | |
| ENST00000586799.1 | DNMT1-019 | 672 | 55aa | ENSP00000467260.1 | Nonsense mediated decay | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000589538.1 | DNMT1-029 | 559 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000593049.1 | DNMT1-021 | 534 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000591798.1 | DNMT1-028 | 521 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000586086.1 | DNMT1-014 | 489 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000586588.1 | DNMT1-004 | 3094 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000585843.1 | DNMT1-018 | 911 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000587197.1 | DNMT1-026 | 809 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000586667.1 | DNMT1-020 | 714 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000589351.1 | DNMT1-024 | 672 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000589349.1 | DNMT1-016 | 603 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000589294.1 | DNMT1-027 | 575 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000589091.1 | DNMT1-025 | 563 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000591239.1 | DNMT1-022 | 550 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000585920.1 | DNMT1-017 | 529 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000587604.1 | DNMT1-023 | 513 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000591764.1 | DNMT1-007 | 341 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
