Description
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) [Source:HGNC Symbol;Acc:6148]
Gene Synonyms
CD11A, LFA-1, LFA1A
Location
Chromosome 16: 30,483,979-30,534,506 forward strand.
GRCh37:CM000678.1
About this gene
This gene has 20 transcripts (splice variants) and 17 paralogues.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000356798.6 | ITGAL-001 | 5213 | 1170aa | ENSP00000349252.5 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS32433 | H3BNL5 I3L468 P20701 | NM_002209.2 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000358164.5 | ITGAL-002 | 4673 | 1086aa | ENSP00000350886.5 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS45461 | H3BNL5 P20701 | NM_001114380.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000433423.2 | ITGAL-004 | 1416 | 404aa | ENSP00000409377.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B4E021 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000454514.2 | ITGAL-201 | 833 | 162aa | ENSP00000408615.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B4DQ77 H3BNL5 I3L468 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000564118.1 | ITGAL-007 | 699 | 203aa | ENSP00000456888.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | H3BNL5 H3BSV1 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000569725.1 | ITGAL-008 | 545 | 41aa | ENSP00000461006.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | I3L468 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000562857.1 | ITGAL-003 | 821 | 162aa | ENSP00000454342.1 | Nonsense mediated decay | B4DQ77 H3BNL5 I3L468 | - | - | |
| ENST00000563615.1 | ITGAL-020 | 575 | 38aa | ENSP00000458739.1 | Nonsense mediated decay | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000562652.1 | ITGAL-010 | 561 | 90aa | ENSP00000456521.1 | Nonsense mediated decay | H3BS37 | - | - | |
| ENST00000568926.1 | ITGAL-009 | 559 | 109aa | ENSP00000457785.1 | Nonsense mediated decay | H3BUT3 | - | - | |
| ENST00000565864.1 | ITGAL-011 | 536 | 55aa | ENSP00000454908.1 | Nonsense mediated decay | H3BNL5 | - | - | |
| ENST00000568012.1 | ITGAL-016 | 575 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000565348.1 | ITGAL-012 | 557 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000566267.1 | ITGAL-022 | 537 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000569570.1 | ITGAL-005 | 496 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000564632.1 | ITGAL-023 | 964 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000564935.1 | ITGAL-017 | 585 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000562020.1 | ITGAL-021 | 561 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000568987.1 | ITGAL-018 | 549 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000566149.1 | ITGAL-015 | 443 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
