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Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
- GO: Anatomical entity
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
External references
Supporting evidence
ID History
- Gene history

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Gene: PDE5A ENSG00000138735

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Description

phosphodiesterase 5A, cGMP-specific [Source:HGNC Symbol;Acc:8784]

Gene Synonyms

CGB-PDE, CN5A, PDE5

Location

Chromosome 4: 120,415,550-120,550,146 reverse strand.

GRCh37:CM000666.1

About this gene

This gene has 12 transcripts (splice variants), 220 orthologues and 20 paralogues.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000354960.3	PDE5A-001	7154	875aa	ENSP00000347046.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS3713	C9JGT3 G5E9C5 O76074 Q4W5L4 Q9P0K4 Q9P0K6	NM_001083.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000394439.1	PDE5A-201	6733	823aa	ENSP00000377957.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		C9JGT3 G5E9C5 Q4W5L4	NM_033437.3	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000264805.5	PDE5A-002	3020	833aa	ENSP00000264805.5	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS34055	C9JGT3 G5E9C5 O76074 Q4W5L4	NM_033430.2	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000503412.1	PDE5A-005	892	185aa	ENSP00000425810.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000420633.1	PDE5A-003	747	224aa	ENSP00000416309.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		C9JGT3	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000512739.1	PDE5A-008	648	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000513594.1	PDE5A-011	572	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000512450.1	PDE5A-012	567	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000502912.1	PDE5A-004	371	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000509612.1	PDE5A-009	738	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000508914.1	PDE5A-007	514	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000512494.1	PDE5A-006	411	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Summary

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