Gene: GPX4 ENSG00000167468

Description

glutathione peroxidase 4 [Source:HGNC Symbol;Acc:4556]

Gene Synonyms

GPx-4, GSHPx-4, MCSP, PHGPx, snGPx, snPHGPx

Location

Chromosome 19: 1,103,936-1,106,787 forward strand.

GRCh37:CM000681.1

About this gene

This gene has 9 transcripts (splice variants), 163 orthologues, 7 paralogues and is associated with 3 phenotypes.

Transcripts

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Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000354171.8	GPX4-002	908	197aa	ENSP00000346103.7	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS42457	P36969 Q6PJX4	NM_002085.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000589115.1	GPX4-011	820	180aa	ENSP00000466872.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000588919.1	GPX4-003	803	260aa	ENSP00000464989.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000585362.2	GPX4-004	754	145aa	ENSP00000473614.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000593032.1	GPX4-006	582	194aa	ENSP00000465828.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete,
ENST00000587648.1	GPX4-009	577	155aa	ENSP00000468349.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000585480.1	GPX4-010	501	166aa	ENSP00000467900.1	Non stop decay		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000592940.1	GPX4-005	1159	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000587932.1	GPX4-012	264	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Gene: GPX4 ENSG00000167468

Summary