Description
mitogen-activated protein kinase kinase 3 [Source:HGNC Symbol;Acc:6843]
Gene Synonyms
MAPKK3, MEK3, MKK3, PRKMK3, SAPKK-2, SAPKK2, SKK2
Location
Chromosome 17: 21,187,984-21,218,552 forward strand.
GRCh37:CM000679.1
About this gene
This gene has 13 transcripts (splice variants) and 6 paralogues.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000342679.4 | MAP2K3-001 | 2303 | 347aa | ENSP00000345083.4 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS11217 | D3DXI2 E9PRZ0 P46734 Q6FI23 | NM_145109.2 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000361818.5 | MAP2K3-201 | 2034 | 318aa | ENSP00000355081.5 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS11218 | D3DXI2 E9PRZ0 P46734 | NM_002756.4 | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000316920.6 | MAP2K3-013 | 1246 | 318aa | ENSP00000319139.6 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS11218 | D3DXI2 E9PRZ0 P46734 | - | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000526076.2 | MAP2K3-016 | 575 | 160aa | ENSP00000434068.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PRZ0 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000527123.1 | MAP2K3-014 | 535 | 136aa | ENSP00000462178.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | J3KRV4 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000529517.1 | MAP2K3-011 | 514 | 101aa | ENSP00000431203.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PMA8 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000395491.2 | MAP2K3-002 | 2401 | 46aa | ENSP00000378869.2 | Nonsense mediated decay | - | - | - | |
| ENST00000496046.1 | MAP2K3-004 | 2089 | 173aa | ENSP00000464043.1 | Nonsense mediated decay | J3QR49 | - | - | |
| ENST00000479129.1 | MAP2K3-006 | 574 | 46aa | ENSP00000463417.1 | Nonsense mediated decay | J3QL77 | - | - | |
| ENST00000483928.2 | MAP2K3-007 | 511 | 46aa | ENSP00000463202.1 | Nonsense mediated decay | J3QL77 | - | - | |
| ENST00000534743.1 | MAP2K3-010 | 541 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000477540.1 | MAP2K3-009 | 927 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000583508.1 | MAP2K3-017 | 607 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
