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Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
- GO: Biological process
- GO: Cellular component
- GO: Molecular function
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
External references
Supporting evidence
ID History
- Gene history

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Gene: MAP2K3 ENSG00000034152

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Description

mitogen-activated protein kinase kinase 3 [Source:HGNC Symbol;Acc:6843]

Gene Synonyms

MAPKK3, MEK3, MKK3, PRKMK3, SAPKK-2, SAPKK2, SKK2

Location

Chromosome 17: 21,187,984-21,218,552 forward strand.

GRCh37:CM000679.1

About this gene

This gene has 13 transcripts (splice variants), 133 orthologues and 35 paralogues.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000342679.4	MAP2K3-001	2303	347aa	ENSP00000345083.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS11217	D3DXI2 E9PRZ0 P46734 Q6FI23	NM_145109.2	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000361818.5	MAP2K3-201	2034	318aa	ENSP00000355081.5	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS11218	D3DXI2 E9PRZ0 P46734	NM_002756.4	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000316920.6	MAP2K3-013	1246	318aa	ENSP00000319139.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS11218	D3DXI2 E9PRZ0 P46734	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000526076.2	MAP2K3-016	575	160aa	ENSP00000434068.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E9PRZ0	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000527123.1	MAP2K3-014	535	136aa	ENSP00000462178.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		J3KRV4	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000529517.1	MAP2K3-011	514	101aa	ENSP00000431203.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E9PMA8	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000395491.2	MAP2K3-002	2401	46aa	ENSP00000378869.2	Nonsense mediated decay		-	-	-
ENST00000496046.1	MAP2K3-004	2089	173aa	ENSP00000464043.1	Nonsense mediated decay		J3QR49	-	-
ENST00000479129.1	MAP2K3-006	574	46aa	ENSP00000463417.1	Nonsense mediated decay		J3QL77	-	-
ENST00000483928.2	MAP2K3-007	511	46aa	ENSP00000463202.1	Nonsense mediated decay		J3QL77	-	-
ENST00000534743.1	MAP2K3-010	541	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000477540.1	MAP2K3-009	927	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000583508.1	MAP2K3-017	607	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Summary

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