Description
cathepsin B [Source:HGNC Symbol;Acc:2527]
Gene Synonyms
APPS, CPSB
Location
Chromosome 8: 11,700,033-11,726,957 reverse strand.
GRCh37:CM000670.1
About this gene
This gene has 35 transcripts (splice variants), 2 paralogues and is associated with 1 phenotype.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000353047.6 | CTSB-001 | 3875 | 339aa | ENSP00000345672.5 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS5986 | E9PHZ5 E9PID0 E9PIS1 E9PJ67 E9PKQ7 E9PKX0 E9PL32 E9PLY3 E9PNL5 E9PQM1 E9PR00 E9PR54 E9PS78 E9PSG5 P07858 Q8TAC7 R4GMQ5 | NM_001908.3 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000434271.1 | CTSB-202 | 3859 | 339aa | ENSP00000415889.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS5986 | E9PHZ5 E9PID0 E9PIS1 E9PJ67 E9PKQ7 E9PKX0 E9PL32 E9PLY3 E9PNL5 E9PQM1 E9PR00 E9PR54 E9PS78 E9PSG5 P07858 Q8TAC7 R4GMQ5 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000345125.3 | CTSB-007 | 2028 | 339aa | ENSP00000342070.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS5986 | E9PHZ5 E9PID0 E9PIS1 E9PJ67 E9PKQ7 E9PKX0 E9PL32 E9PLY3 E9PNL5 E9PQM1 E9PR00 E9PR54 E9PS78 E9PSG5 P07858 Q8TAC7 R4GMQ5 | NM_147781.2 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000453527.2 | CTSB-006 | 2011 | 339aa | ENSP00000409917.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS5986 | E9PHZ5 E9PID0 E9PIS1 E9PJ67 E9PKQ7 E9PKX0 E9PL32 E9PLY3 E9PNL5 E9PQM1 E9PR00 E9PR54 E9PS78 E9PSG5 P07858 Q8TAC7 R4GMQ5 | NM_147783.2 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000533455.1 | CTSB-002 | 2009 | 339aa | ENSP00000432244.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS5986 | E9PHZ5 E9PID0 E9PIS1 E9PJ67 E9PKQ7 E9PKX0 E9PL32 E9PLY3 E9PNL5 E9PQM1 E9PR00 E9PR54 E9PS78 E9PSG5 P07858 Q8TAC7 R4GMQ5 | NM_147782.2 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000534510.1 | CTSB-005 | 1989 | 339aa | ENSP00000434217.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS5986 | E9PHZ5 E9PID0 E9PIS1 E9PJ67 E9PKQ7 E9PKX0 E9PL32 E9PLY3 E9PNL5 E9PQM1 E9PR00 E9PR54 E9PS78 E9PSG5 P07858 Q8TAC7 R4GMQ5 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000415599.2 | CTSB-201 | 1772 | 110aa | ENSP00000411254.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PCB3 E9PID0 E9PIS1 E9PJ67 E9PKX0 E9PL32 E9PR00 E9PR54 E9PS78 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000531089.1 | CTSB-004 | 1436 | 339aa | ENSP00000433215.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS5986 | E9PHZ5 E9PID0 E9PIS1 E9PJ67 E9PKQ7 E9PKX0 E9PL32 E9PLY3 E9PNL5 E9PQM1 E9PR00 E9PR54 E9PS78 E9PSG5 P07858 Q8TAC7 R4GMQ5 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000530640.2 | CTSB-003 | 1389 | 339aa | ENSP00000435105.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS5986 | E9PHZ5 E9PID0 E9PIS1 E9PJ67 E9PKQ7 E9PKX0 E9PL32 E9PLY3 E9PNL5 E9PQM1 E9PR00 E9PR54 E9PS78 E9PSG5 P07858 Q8TAC7 R4GMQ5 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000533572.1 | CTSB-017 | 975 | 170aa | ENSP00000433995.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PHZ5 E9PID0 E9PIS1 E9PJ67 E9PKQ7 E9PKX0 E9PL32 E9PLY3 E9PNL5 E9PR00 E9PR54 E9PS78 E9PSG5 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000534382.1 | CTSB-023 | 764 | 70aa | ENSP00000435260.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PID0 E9PIS1 E9PKX0 E9PL32 E9PR00 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000534636.1 | CTSB-015 | 633 | 175aa | ENSP00000436159.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PHZ5 E9PID0 E9PIS1 E9PJ67 E9PKQ7 E9PKX0 E9PL32 E9PLY3 E9PNL5 E9PQM1 E9PR00 E9PR54 E9PS78 E9PSG5 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000527243.1 | CTSB-021 | 580 | 143aa | ENSP00000434725.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PID0 E9PIS1 E9PJ67 E9PKQ7 E9PKX0 E9PL32 E9PNL5 E9PR00 E9PR54 E9PS78 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000524500.1 | CTSB-016 | 573 | 98aa | ENSP00000436074.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PID0 E9PIS1 E9PKX0 E9PL32 E9PR00 E9PR54 E9PS78 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000532656.2 | CTSB-030 | 573 | 70aa | ENSP00000431143.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PID0 E9PIS1 E9PKX0 E9PL32 E9PR00 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000532392.1 | CTSB-024 | 570 | 20aa | ENSP00000432408.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PR00 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000530296.1 | CTSB-019 | 561 | 165aa | ENSP00000435074.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PHZ5 E9PID0 E9PIS1 E9PJ67 E9PKQ7 E9PKX0 E9PL32 E9PLY3 E9PNL5 E9PR00 E9PR54 E9PS78 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000526195.1 | CTSB-020 | 560 | 148aa | ENSP00000436627.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PHZ5 E9PID0 E9PIS1 E9PJ67 E9PKQ7 E9PKX0 E9PL32 E9PNL5 E9PR00 E9PR54 E9PS78 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000526645.1 | CTSB-027 | 559 | 136aa | ENSP00000431518.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PID0 E9PIS1 E9PJ67 E9PKQ7 E9PKX0 E9PL32 E9PR00 E9PR54 E9PS78 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000531502.1 | CTSB-013 | 557 | 92aa | ENSP00000435886.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PID0 E9PIS1 E9PKX0 E9PL32 E9PR00 E9PS78 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000528965.1 | CTSB-032 | 556 | 55aa | ENSP00000433929.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PID0 E9PIS1 E9PR00 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000527215.2 | CTSB-014 | 545 | 68aa | ENSP00000433379.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PID0 E9PIS1 E9PL32 E9PR00 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000505496.2 | CTSB-033 | 540 | 101aa | ENSP00000435650.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PID0 E9PIS1 E9PJ67 E9PKX0 E9PL32 E9PR00 E9PR54 E9PS78 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000534149.1 | CTSB-018 | 524 | 143aa | ENSP00000436122.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PID0 E9PIS1 E9PJ67 E9PKQ7 E9PKX0 E9PL32 E9PNL5 E9PR00 E9PR54 E9PS78 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000524654.1 | CTSB-025 | 368 | 32aa | ENSP00000432077.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PID0 E9PR00 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000531551.1 | CTSB-011 | 1855 | 110aa | ENSP00000436456.1 | Nonsense mediated decay | E9PCB3 E9PID0 E9PIS1 E9PJ67 E9PKX0 E9PL32 E9PR00 E9PR54 E9PS78 | - | - | |
| ENST00000526481.2 | CTSB-042 | 660 | 76aa | ENSP00000473301.1 | Nonsense mediated decay | R4GMQ5 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000525076.1 | CTSB-026 | 550 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000530290.1 | CTSB-038 | 498 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000530624.1 | CTSB-039 | 430 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000533110.1 | CTSB-037 | 399 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000420692.2 | CTSB-041 | 2230 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000532409.1 | CTSB-036 | 839 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000532370.1 | CTSB-035 | 693 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000525315.1 | CTSB-034 | 586 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
