Description
protein tyrosine kinase 2 [Source:HGNC Symbol;Acc:9611]
Gene Synonyms
FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK
Location
Chromosome 8: 141,667,999-142,012,315 reverse strand.
GRCh37:CM000670.1
About this gene
This gene has 59 transcripts (splice variants) and 13 paralogues.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000340930.3 | PTK2-011 | 4414 | 1065aa | ENSP00000341189.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS56557 | E5RFW9 E5RG66 E5RG80 E5RG86 E5RGA6 E5RH01 E5RH08 E5RH48 E5RHD8 E5RHK7 E5RI72 E5RIK4 E5RJQ2 Q05397 | NM_001199649.1 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000522684.1 | PTK2-001 | 4955 | 1052aa | ENSP00000429911.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS6381 | B4DWJ1 E5RFW9 E5RG66 E5RG80 E5RG86 E5RGA6 E5RH01 E5RH08 E5RH48 E5RHD8 E5RHK7 E5RI72 E5RIK4 E5RJQ2 Q05397 | NM_153831.3 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000517887.1 | PTK2-008 | 4661 | 1096aa | ENSP00000429082.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B4DWJ1 E5RFW9 E5RG66 E5RG80 E5RG86 E5RGA6 E5RH01 E5RH08 E5RH48 E5RHD8 E5RHK7 E5RI72 E5RIK4 E5RJQ2 E7ESA6 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000395218.2 | PTK2-201 | 4492 | 1065aa | ENSP00000378644.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RFW9 E5RG66 E5RG80 E5RG86 E5RGA6 E5RH01 E5RH08 E5RH48 E5RHD8 E5RHK7 E5RI72 E5RIK4 E5RJQ2 J3QT16 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000519419.1 | PTK2-007 | 4439 | 1096aa | ENSP00000429129.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B4DWJ1 E5RFW9 E5RG66 E5RG80 E5RG86 E5RGA6 E5RH01 E5RH08 E5RH48 E5RHD8 E5RHK7 E5RI72 E5RIK4 E5RJQ2 E7ESA6 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000521059.1 | PTK2-057 | 4405 | 1052aa | ENSP00000429474.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS6381 | B4DWJ1 E5RFW9 E5RG66 E5RG80 E5RG86 E5RGA6 E5RH01 E5RH08 E5RH48 E5RHD8 E5RHK7 E5RI72 E5RIK4 E5RJQ2 Q05397 | NM_005607.4 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000519654.1 | PTK2-010 | 4129 | 1017aa | ENSP00000429929.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RFW9 E5RG66 E5RG86 E5RGA6 E5RH01 E5RH08 E5RH48 E5RHD8 E5RI72 E5RIK4 Q8IYN9 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000535192.1 | PTK2-202 | 4127 | 1006aa | ENSP00000438009.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RFW9 E5RG66 E5RG86 E5RGA6 E5RH01 E5RH08 E5RH48 E5RHD8 E5RI72 E5RIK4 Q8IYN9 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000517712.1 | PTK2-004 | 3351 | 115aa | ENSP00000430916.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RHD8 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000519465.1 | PTK2-005 | 3279 | 680aa | ENSP00000429170.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B4DWJ1 E5RG80 E5RHD8 E5RHK7 E5RIR5 E5RJQ2 E9PEI4 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000523539.1 | PTK2-002 | 3236 | 724aa | ENSP00000428492.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B4DWJ1 E5RG80 E5RHD8 E5RHK7 E5RJQ2 H0YB16 Q8N9D7 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000538769.1 | PTK2-203 | 3236 | 720aa | ENSP00000445742.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B4DWJ1 E5RG80 E5RHD8 E5RHK7 E5RJQ2 Q8N9D7 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000521986.1 | PTK2-009 | 2393 | 753aa | ENSP00000430603.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B4DH13 E5RG80 E5RHD8 E5RHK7 E5RJQ2 H0YBZ1 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000430260.2 | PTK2-006 | 1940 | 362aa | ENSP00000403416.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B4DWJ1 E5RG80 E5RHD8 E5RHK7 E5RJQ2 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000519881.1 | PTK2-037 | 863 | 121aa | ENSP00000430277.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RFW9 E5RG66 E5RH01 E5RH08 E5RH48 E5RI72 E5RIK4 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000523803.1 | PTK2-032 | 750 | 120aa | ENSP00000429530.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RG66 E5RH01 E5RH08 E5RH48 E5RI72 E5RIK4 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000521562.1 | PTK2-019 | 678 | 132aa | ENSP00000431106.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RHK7 E5RJQ2 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000521332.1 | PTK2-039 | 630 | 65aa | ENSP00000429409.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RH08 E5RIK4 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000523435.1 | PTK2-015 | 629 | 120aa | ENSP00000430828.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RI03 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000520045.1 | PTK2-044 | 602 | 117aa | ENSP00000430044.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RH01 E5RH08 E5RH48 E5RIK4 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000523388.1 | PTK2-020 | 581 | 67aa | ENSP00000429702.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RHK7 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000519024.1 | PTK2-053 | 576 | 168aa | ENSP00000428232.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RJI4 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000520828.1 | PTK2-041 | 574 | 59aa | ENSP00000427762.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RG86 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000520151.1 | PTK2-054 | 573 | 124aa | ENSP00000428482.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RI29 E5RIR5 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000520892.1 | PTK2-038 | 571 | 121aa | ENSP00000427904.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RFW9 E5RG66 E5RH01 E5RH08 E5RH48 E5RI72 E5RIK4 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000517453.1 | PTK2-043 | 571 | 117aa | ENSP00000430951.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RH01 E5RH08 E5RH48 E5RIK4 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000520475.1 | PTK2-033 | 570 | 156aa | ENSP00000428792.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RFW9 E5RG66 E5RGA6 E5RH01 E5RH08 E5RH48 E5RI72 E5RIK4 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000522424.1 | PTK2-047 | 569 | 133aa | ENSP00000427774.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RG80 E5RHK7 E5RJQ2 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000522950.1 | PTK2-014 | 548 | 67aa | ENSP00000429437.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RII9 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000521907.1 | PTK2-035 | 542 | 119aa | ENSP00000427795.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RG66 E5RH01 E5RH08 E5RH48 E5RIK4 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000521395.1 | PTK2-034 | 540 | 107aa | ENSP00000429907.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RH08 E5RH48 E5RIK4 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000524357.1 | PTK2-055 | 535 | 122aa | ENSP00000429001.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RH08 E5RIK4 E5RJP0 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000523679.1 | PTK2-040 | 504 | 14aa | ENSP00000429028.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000524040.1 | PTK2-045 | 475 | 51aa | ENSP00000430037.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RH08 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000524257.1 | PTK2-042 | 430 | 8aa | ENSP00000431023.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000519993.1 | PTK2-013 | 4388 | 66aa | ENSP00000428570.1 | Nonsense mediated decay | E5RG54 E5RH08 E5RIK4 | - | - | |
| ENST00000524202.1 | PTK2-003 | 3014 | 319aa | ENSP00000429023.1 | Nonsense mediated decay | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000521250.1 | PTK2-049 | 592 | 72aa | ENSP00000427972.1 | Nonsense mediated decay | H0YAS0 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000521029.1 | PTK2-051 | 584 | 79aa | ENSP00000429958.1 | Nonsense mediated decay | E5RGP1 E5RIR5 | - | - | |
| ENST00000521791.1 | PTK2-031 | 556 | 66aa | ENSP00000427825.1 | Nonsense mediated decay | E5RG54 E5RH08 E5RIK4 | - | - | |
| ENST00000521981.1 | PTK2-052 | 552 | 128aa | ENSP00000428593.1 | Nonsense mediated decay | H0YB33 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000523670.1 | PTK2-050 | 542 | 72aa | ENSP00000428380.1 | Nonsense mediated decay | E5RIR5 | - | - | |
| ENST00000523067.1 | PTK2-046 | 488 | 66aa | ENSP00000429895.1 | Nonsense mediated decay | E5RG54 E5RH08 E5RIK4 | - | - | |
| ENST00000519635.1 | PTK2-029 | 578 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000523746.1 | PTK2-026 | 574 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000520460.1 | PTK2-016 | 572 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000518509.1 | PTK2-048 | 569 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000523474.1 | PTK2-027 | 567 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000519361.1 | PTK2-025 | 553 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000521985.1 | PTK2-018 | 538 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000521172.1 | PTK2-028 | 507 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000523805.1 | PTK2-017 | 440 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000520843.1 | PTK2-024 | 438 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000523797.1 | PTK2-030 | 405 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000519899.1 | PTK2-023 | 762 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000520917.1 | PTK2-021 | 653 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000523675.1 | PTK2-036 | 650 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000510126.2 | PTK2-022 | 580 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000518173.1 | PTK2-056 | 441 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
